Results 191 to 200 of about 743,545 (259)

Biomimetic Macrophage Cell Membrane‐Based Nanoparticles for Effective Treatment of Glioblastoma Through Boron Neutron Capture Therapy Combined With Immunotherapy

Advanced Science, EarlyView.
ABSTRACT Glioblastoma multiforme (GBM) remains largely incurable due to the blood‐brain barrier (BBB) and immunosuppressive microenvironment. While boron neutron capture therapy (BNCT) selectively eradicates tumor cells via 10B(n, α)‐7Li reactions, its clinical potential in GBM is unrealized because of the suboptimal pharmacokinetics of conventional ...
Jiawen Chen, Haoyu You, Hefa Huang, Huihui Chai, Ruize Zhu, Yun Guan, Qisheng Tang, Tianwen Li, Shan Jiang, Houshi Xu, Peng Wang, Yue Wang, Maoyuan Sun, Beining Liu, Zhen Li, Yulai Zeng, Weiqiu Ping, Yanlin Teng, Songlin Yan, Qinghui Li, Long Gu, Tao Sun, Zhifeng Shi   +22 more
wiley   +1 more source

SURE gel electrophoresis: A method for improved detection and purification of dilute nucleic acid samples. [PDF]

Anal Biochem
Sowersby DS, Lewis LK.
europepmc   +1 more source

UBE2O Drives Immune Evasion and Radioimmunotherapy Resistance in Lung Cancer by Degrading CDKL1 to Induce PD‐L1 Transcription

Advanced Science, EarlyView.
UBE2O targets CDKL1 for the degradation to upregulate PD‐L1 expression and promotes resistance to radioimmunotherapy in lung cancer, supporting the potential of targeting UBE2O as a promising therapeutic strategy. ABSTRACT Resistance to radioimmunotherapy is one of the primary causes of treatment failure in lung cancer patients; however, the underlying
Huichan Xue, Xiaohua Jie, Zhiwei Liu, Ruoxin Fang, Shuo Wu, Xiaorong Dong, Shuangbing Xu   +6 more
wiley   +1 more source

Single-tube Ptprc SNP genotyping of JAXBoy (CD45.1) and C57BL/6J (CD45.2) mice by endpoint PCR and gel electrophoresis. [PDF]

Mol Cell Probes
Ryan CE, Salvetti TR, Baum IR, Figueroa BA, LeBere BE, Alberti MO.   +5 more
europepmc   +1 more source

Quantitative Analysis of Genomic DNA Degradation of E. coli Using Automated Gel Electrophoresis under Various Levels of Microwave Exposure. [PDF]

Gels
Pandey A, Momeni O, Pandey P.
europepmc   +1 more source

Purification of Native Dentilisin Complex from Treponema denticola by Preparative Continuous Polyacrylamide Gel Electrophoresis and Functional Analysis by Gelatin Zymography. [PDF]

Bio Protoc
Kamarajan P, Timm JC, Goetting-Minesky MP, Malone ET, Ganther S, Radaic A, Tafolla C, Fenno JC, Kapila YL.   +8 more
europepmc   +1 more source

An easy tool to monitor the elemental steps of in vitro translation via gel electrophoresis of fluorescently labeled small peptides. [PDF]

RNA
Marina VI, Bidzhieva M, Tereshchenkov AG, Orekhov D, Sagitova VE, Sumbatyan NV, Tashlitsky VN, Ferberg AS, Maviza TP, Kasatsky P, Tolicheva O, Paleskava A, Polshakov VI, Osterman IA, Dontsova OA, Konevega AL, Sergiev PV.   +16 more
europepmc   +1 more source

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Difference gel electrophoresis

Electrophoresis, 2009
AbstractDifference gel electrophoresis (DIGE) was invented to circumvent the inherent variability of 2‐DE. This variability is a natural consequence of separating thousands of proteins over a large space, such as a 15×20 cm slab of polyacrylamide gel.
Jonathan Minden
exaly   +3 more sources

Electrophoresis in gel channels

ELECTROPHORESIS, 2005
AbstractWe describe a novel approach to generate dynamic pH gradients suited to fractionate or purify samples of biomolecules or particles such as proteins and viruses in tiny volumes. The method combines diffusion and electromigration between micro‐scaled channels embedded in hydrogel.
Rolf, Hagedorn, Thomas, Schnelle, Torsten, Müller, Ingo, Scholz, Kristian, Lange, Maila, Reh   +5 more
openaire   +2 more sources

Micro gel electrophoresis

Clinica Chimica Acta, 1967
Abstract A modificed disc electrophoresis method is described in detail. The gel columns were made in tubes of 0.9 mm internal diameter. The method requires a total protein content of 0.01 mg. Samples containing 80–100 mg protein per 100 ml can be studied without concentration. Resolution is as good as in the original macro method.
U, Krause, V, Raunio
openaire   +2 more sources