Results 41 to 50 of about 1,138,639 (256)

Compensation Of Smile Effect Distortion In Electrophoretic Gel Image [PDF]

, 2015
This paper is engaged in the issue of automatic detection and removal of smile effect geometrical distortion in agarose gel electrophoresis images. Based on created databank of electrophoretic phantoms, an algorithm that is able to repair mentioned smile
Dvořáček, T.
core  

Determination of association constants between 5 '-guanosine monophosphate gel and aromatic compounds by capillary electrophoresis [PDF]

, 2013
Hydro gel formed by 5'-guanosine monophosphate (GMP) in the presence of a potassium ion is expected to exhibit interesting selectivity in capillary electrophoretic separations.
Alberty, Barker, Case, Chen, Chinai, Cohen, Cohen, Cohen, Davis, Dobashi, Dong, Dong, Dowling, Gozel, Heiger, Hjertén, Honda, Jorgenson, Kaori Yamaguchi, Khaledi, Kuhn, Kuhn, Mikkers, Muijselaar, Nobuyuki Takeyasu, Rundlett, Sepulveda, Smith, Takashi Kaneta, Terabe, Ueda, Widhalm, Šponer   +32 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Diversity and Dynamics of Indigenous \u3cem\u3eRhizobium japonicum\u3c/em\u3e Populations [PDF]

, 1980
A simple method, based upon the separation of cellular proteins by sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis, has been devised for distinguishing between isolates of Rhizobium japonicum.
Brill, Winston J., Noel, K. Dale
core   +1 more source

Genetic characterization of Mycobacterium avium isolates recovered from humans and animals in Australia [PDF]

, 1996
Genetic relationships amongst 115 mainly Australian isolates of Mycobacterium avium were assessed using multilocus enzyme electrophoresis (MEE). The isolates were divided into 58 electrophoretic types (ETs), with a mean genetic diversity of 0·29 ...
Feizabadi, M.M., Robertson, I.D., Cousins, D.V., Dawson, D., Chew, W., Gilbert, G.L., Hampson, D.J.   +6 more
core   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Gel-Electrophoresis and Diffusion of Ring-Shaped DNA

, 1997
A model for the motion of ring-shaped DNA in a gel is introduced and studied by numerical simulations and a mean-field approximation. The ring motion is mediated by finger-shaped loops (hernias) that move in an amoeba-like fashion around the gel ...
A. R. Kholkov, B. Alberts, B. H. Zimm, B. H. Zimm, C. Godréche, C. Heller, D. C. Schwartz, David Mukamel, E. M. Sevick, G. F. Carle, G. Parisi, G. W. Slater, J. Klein, J. M. Deutsch, J. P. de Gennes, M. Doi, M. E. Cates, M. R. Evans, M. R. Evans, M. Rubinstein, M. Wang, O. J. Lumpkin, P. Serwer, S. B. Smith, S. Gurrieri, S. Levene, S. Mickel, S. P. Obukhov, T. A. J. Duke, T. A. J. Duke, T. A. J. Duke, T. Duke, U. Alon, Uri Alon, W. D. Volkmuth, W. D. Volkmuth   +35 more
core   +2 more sources

Computer simulation of pulsed field gel runs allows the quantitation of radiation-induced double-strand breaks in yeast [PDF]

, 1994
A procedure for the quantification of double-strand breaks in yeast is presented that utilizes pulsed field gel electrophoresis (PFGE) and a comparison of the observed DNA mass distribution in the gel lanes with calculated distributions.
Ahn, Albrecht M. Kellerer, Alfred Kraxenberger, Anna A. Friedl, Averbeck, Blöcher, Blöcher, Carle, Chu, Contopoulou, Elia, Frankenberg-Schwager, Friedl, Gardiner, Geigl, Geigl, Gemmill, Iliakis, Kunz, Link, Noolandi, Noolandi, Ribeiro, Sakurada, Schulz, Schwartz, Slater, Stamato, Sutherland, Ward   +29 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source