Results 141 to 150 of about 2,108,289 (404)

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

Dependence of stacking direction on mechanical properties of gels and plastics formed by 3D printing

open access: yesNihon Kikai Gakkai ronbunshu, 2017
In this work, we present a comparison of the mechanical properties of 3D printed structures with respect to the printing orientation for 3D gel printer "SWIM-ER" and FDM (Fused Deposition Modeling) 3D printer with a result that the fracture ...
Takafumi OTA   +6 more
doaj   +1 more source

Procedure to prepare transparent silica gels [PDF]

open access: yes, 1987
This invention relates to the production of silica gels and in particular to a process for the preparation of silica gels which can be used as a crystal growth medium that simulates the convectionless environment of space to produce structurally perfect ...
Barber, Patrick G., Simpson, Norman R.
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

PROTEOMIC ANALYSIS OF TWO DIFFERENT STATES OF NAEGLERIA FOWLERI [PDF]

open access: yes, 2011
Naegleria fowleri are free-living ameboflagellates found in soil and freshwater habitats throughout the world that cause a fatal disease in humans called Primary Amoebic Meningoencephalitis (PAM).
Park, Hong
core   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

The degree of tooth colour change after using different concentrations of carbamide peroxide [PDF]

open access: yesScripta Medica, 2019
Background: Depending on the cause of discoloration, bleaching materials and other factors, vital dental bleaching techniques may be professional (in-office dental bleaching), at-home night-guard bleaching and combined.
Knežević Nataša   +6 more
doaj  

Weakly nonlinear rheology of transiently crosslinked biopolymer gels [PDF]

open access: yes, 2010
Recent experimental investigations have revealed a non-Maxwellian absorption pattern in the rheological spectra of actin gels, which was interpreted in terms of transient bonds.
Kroy, Klaus, Wolff, Lars
core  

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