Results 151 to 160 of about 2,108,289 (404)
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
Stress Relaxation of Near-Critical Gels
, 2000 The time-dependent stress relaxation for a Rouse model of a crosslinked polymer melt is completely determined by the spectrum of eigenvalues of the connectivity matrix. The latter has been computed analytically for a mean-field distribution of crosslinks.
Aspelmeier, Timo +3 more
core +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Structuring polymer gels via catalytic reactions
, 2016 We use computer simulations to investigate how a catalytic reaction in a polymer sol can induce the formation of a polymer gel. To this aim we consider a solution of homopolymers in which freely-diffusing catalysts convert the originally repulsive A ...
Hugouvieux, Virginie, Kob, Walter
core +1 more source
On the Dephosphorylation and Deamination of Adenosine Triphosphate by Actomyosin Gel. [PDF]
, 1954 Adam Deutsch +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban +12 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
GelsOxidative stress is one of the main factors affecting food stability; therefore, antioxidant additives are generally used as food supplements for shelf-life improvement.
Olimpia Pitirollo +4 more
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 1979 H. Towbin, T. Staehelin, J. Gordon
semanticscholar +1 more source