Results 51 to 60 of about 1,604 (182)

Abirateron (neues Anwendungsgebiet) [PDF]

Das erneute Verfahren zu Afatinib (Giotrif®) bei Patienten mit nichtkleinzelligem Lungenkarzinom und aktivierenden EGFR-Mutationen wird nach Ablauf der in der Erstbewertung vom 8. Mai 2014 festgesetzten Frist durchgeführt.
Honecker, Friedemann, Kaiser, U., Wörmann, Bernhard, Deutsche Gesellschaft für Hämatologie und Medizinische Onkologie, Deutschland. Gemeinsamer Bundesausschuss   +4 more
core   +5 more sources

Systemische immunmodulierende Therapien der epidermalen Nekrolyse (Stevens‐Johnson‐Syndrom/toxisch epidermale Nekrolyse): Systematische Übersicht und Metaanalyse

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 1, Page 34-43, January 2026.
Zusammenfassung Hintergrund und Ziele Epidermale Nekrolyse ist eine seltene, aber schwere Hautreaktion mit hoher Letalität. Zur Wirksamkeit systemischer immunmodulatorischer Therapien (SIT) liegt wenig Evidenz vor. Ziel unserer systematischen Übersichtsarbeit war der Vergleich von SIT mit supportiver Therapie oder untereinander.
Ruben Heuer, Maren Paulmann, Maja Mockenhaupt, Alexander Nast   +3 more
wiley   +1 more source

Generierung & Auswertung versorgungsnaher Daten

Monitor Versorgungsforschung
Im Januar dieses Jahres hat der Gemeinsame Bundesausschuss (G-BA) das Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) mit einer wissenschaftlichen Ausarbeitung zur Methodik bei der Generierung und Auswertung versorgungsnaher ...
Peter Stegmaier
doaj   +1 more source

Developing an Evidence‐Based and Patient‐Centred Care Concept to Address Deficits in German Primary Care of Venous Leg Ulcers: Results of an Expert Survey Within the ULCUS CRURIS CARE Project

International Wound Journal, Volume 23, Issue 1, January 2026.
ABSTRACT Venous leg ulcers (VLU) account for the majority of chronic wounds, with an estimated rise in prevalence due to demographic change. Care often does not comply with evidence, and patients remain passive and uninformed. To support general practice VLU care, the ‘UlcusCrurisCare’ (UCC) project developed a multimodal intervention comprising ...
Thomas Fleischhauer, Regina Poß‐Doering, Nina Sander, Gunter Laux, Joachim Szecsenyi, Attila Altiner, Michel Wensing, Jonas D. Senft   +7 more
wiley   +1 more source

Exploring Barriers to Periodontal Treatment Adherence in Patients With Periodontitis to Inform Development of a Digital Companion: A Qualitative Study

Journal of Clinical Periodontology, Volume 53, Issue 1, Page 58-71, January 2026.
ABSTRACT Aim The objectives of this study were to gain a comprehensive understanding of patients' barriers to adherence to periodontal treatment and to derive intervention functions for a digital companion to support them through their therapy journey.
Lina Weinert, Nihad El Sayed, Michel Wensing, Bettina Dannewitz, Stefan Listl   +4 more
wiley   +1 more source

Effects of Exercise Duration and Intensity on Maximal Exercise Capacity Over 6 Months in Coronary Heart Disease and Type 2 Diabetes—A Secondary Analysis of the LeIKDTrial

Scandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 1, January 2026.
ABSTRACT Exercise training is recommended in coronary heart disease (CHD) and type 2 diabetes (T2DM) patients alike; however, uncertainty remains on the influence of exercise intensity and duration in older patients with both entities. To address this, we performed a secondary analysis including 201 patients (67.9 ± 8.2 years; 84.1% men) from the LeIKD
Felix Gass, Sophia M. Dinges, Isabel Fegers‐Wustrow, Felix Freigang, Patrizia Maier, Matthias Arnold, Ephraim B. Winzer, Frank Edelmann, Oliver Wolfram, Julia Brandts, Bernd Wolfarth, Marcus Dörr, Rolf Wachter, Björn Hackenberg, Sarah Rust, Thomas Nebling, Volker Amelung, Martin Halle, Stephan Mueller   +18 more
wiley   +1 more source

Early and Sustained Shift in Headache Day Frequency Following Eptinezumab Treatment in Adults With Migraine for Whom 2–4 Previous Preventive Treatments Have Failed: A Post Hoc Analysis of the Randomized DELIVER Trial

European Journal of Neurology, Volume 32, Issue 12, December 2025.
This post hoc analysis of data from the DELIVER trial—which had an 88% completion rate across the placebo‐controlled and extension periods—suggests that eptinezumab administration in people with the most burdensome migraine subtypes (chronic and high‐frequency episodic migraine) induces a shift of MHDs towards less burdensome subtypes.
Cristina Tassorelli, Amaal J. Starling, Susanne F. Awad, Xin Ying Lee, Line Pickering Boserup, Divya Asher, Seema Soni‐Brahmbhatt, Bjørn Sperling, Peter J. Goadsby   +8 more
wiley   +1 more source

Vergleich der körperlichen Funktion zur Entlassung von Patienten mit herkömmlicher vs. intensivierter physiotherapeutischer Behandlung (gemäß GBA-Beschluss) nach proximaler Femurfraktur [PDF]

, 2022
Kamin, K, Krüger, A, Marx, C, Bortkevicius, E, Postler, A, Beyer, F, Lützner, C   +6 more
core   +1 more source

Wearable Monitoring Captures Sleep Disturbances in Patients With Chronic Inflammatory Demyelinating Polyneuropathy

Journal of the Peripheral Nervous System, Volume 30, Issue 4, December 2025.
ABSTRACT Background and Aims Previous studies suggest that patients with chronic inflammatory demyelinating polyneuropathy (CIDP) experience impaired sleep, contributing to fatigue. Traditional methods like polysomnography or questionnaires are resource‐intensive and may not capture sleep in natural settings.
Jan Voth, Charlotte von Gall, Noëmi Gmahl, Noah M. Werner, Gerd Meyer zu Hörste, Sven G. Meuth, Marc Pawlitzki, Lars Masanneck   +7 more
wiley   +1 more source

Barriers and Facilitators of Sleep Restriction Therapy in Internet‐Delivered CBT‐I: A Qualitative Content Analysis and the Development of a Treatment Path Model

Journal of Sleep Research, Volume 34, Issue 6, December 2025.
ABSTRACT Sleep Restriction Therapy (SRT) is a core component of cognitive behavioural therapy for insomnia (CBT‐I). Yet, adherence to SRT can be a major challenge for patients. As this challenge is evident in conventional face‐to‐face therapy, it raises the question of adherence to SRT in internet‐delivered therapy.
Laura Simon, Lisa Steinmetz, Nils Berghoff, Charlotte Rehm, Lena‐Marie Neumann, Ann‐Marie Küchler, Dieter Riemann, David Daniel Ebert, Kai Spiegelhalder, Harald Baumeister   +9 more
wiley   +1 more source