Results 101 to 110 of about 10,184 (280)

An Object memory for an object-oriented database management system [PDF]

open access: yes, 1988
Ankara : The Department of Computer Engineering and Information Sciences and the Institute of Engineering and Sciences of Bilkent Univ. , 1988.Thesis (Master's) -- Bilkent University), 1988.Includes bibliographical references leaves 86-89.Object-oriented
Kesim, F Nihan
core  

An Insulin‐Exosome‐TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li   +15 more
wiley   +1 more source

Google Sets, Google Suggest, and Google Search History: Three More Tools for the Reference Librarian's Bag of Tricks [PDF]

open access: yes, 2008
This article examines the features, quirks, and uses of Google Sets, Google Suggest, and Google Search History and argues that these three lesser-known Google tools warrant inclusion in the resourceful reference librarian’s bag of ...
Cirasella, Jill
core  

Decoding the Integrated Stress Response of Pancreatic Cancer: Identifying a Serine‐dependent Tumor Subset Under Metabolic Relationships With CAFs.

open access: yesAdvanced Science, EarlyView.
Researchers identified a pancreatic cancer subset with low global protein synthesis but heightened translation of stress‐response genes like ATF4, rendering cells resistant to chemotherapy and apoptosis. These tumors depend on serine and cysteine from surrounding cancer‐associated fibroblasts (CAFs), which shift to produce serine by curbing collagen ...
Sauyeun Shin   +25 more
wiley   +1 more source

Towards a new package dependency model [PDF]

open access: yes, 2014
International audienceSmalltalk originally did not have a package manager. Each Smalltalk implementation defined its own with more or less functionalities.
Cassou, Damien   +2 more
core   +2 more sources

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

open access: yesAdvanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou   +17 more
wiley   +1 more source

Hard Assets: The Returns on Rare Diamonds and Gems [PDF]

open access: yes
This paper examines the investment performance of diamonds and other gems (sapphires, rubies, and emeralds) over the period 1999-2010, using a novel data set of auction transactions.
Renneboog, L.D.R., Spaenjers, C.
core   +1 more source

fMRI Evidence for Modality-Specific Processing of Conceptual Knowledge on Six Modalities [PDF]

open access: yes, 2003
Traditional theories assume that amodal representations, such as feature lists and semantic networks, represent conceptual knowledge about the world. According to this view, the sensory, motor, and introspective states that arise during perception and ...
Barsalou, L.W.   +4 more
core  

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

open access: yesAdvanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li   +12 more
wiley   +1 more source

First experience with single-source, dual-energy CCTA for monochromatic stent imaging [PDF]

open access: yes, 2017
Aims Single-source, dual-energy coronary computed tomography angiography (CCTA) with monochromatic image reconstruction allows significant noise reduction.
Buechel, Ronny R.   +8 more
core  

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