Results 81 to 90 of about 14,278 (336)
Advanced Science, EarlyView.Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun +7 more
wiley +1 more source
The Discourse of Fairyland in the Dream Vision of the Middle English Pearl [PDF]
, 2017 The Middle English poem Pearl is a mixture of a number of genres. Opening like an elegy, with its initial stanzas heavily indebted to courtly love poetry, it proceeds towards a dream vision that launches into a theological debate concluded by an ...
Spyra, Piotr
core
Translational Lung Cancer Research, 2020 Background In China, platinum-based doublet chemotherapy is the standard treatment for patients who have unresectable stage III non-small cell lung cancer (NSCLC), administered with radiotherapy on either a concurrent or sequential basis.
Qing Zhou +10 more
semanticscholar +1 more source
LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1
Advanced Science, EarlyView.LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li +12 more
wiley +1 more source
Advanced Science, EarlyView.CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He +17 more
wiley +1 more source
‘Eye-Like Radiance’: The Depiction of Gemstones in Roman Wall Painting
Arts, 2019 The study of ornament in Greek and Roman art has been the focus of increasing scholarly interest over the last decade, with many publications shedding new light on the dynamics of ornatus in antiquity, and the discourses that shaped and situated it ...
Ruth Allen
doaj +1 more source
The Merlin OMS Benchmark - Definition, Implementations and Results [PDF]
, 2002 The bottleneck of highly integrated software development environments (SDEs) could still be the use of an underlying central data store. An environment is called highly integrated, if the included tools support most of the life-cycle phases and ...
Emmerich, Wolfgang, Kampmann, Martin
core
Advanced Science, EarlyView.By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang +16 more
wiley +1 more source
, 2007 The sapphire shop business is an extension of John Tollison\u27s lifelong avocation towards gemstones in general and sapphires in particular. It is a blend of both decisions concerning the expanding financial strains of the business, with two alternative
Dannels, Jeff, Lopez, Raymond H.
core +1 more source
The multiplier accelerator theory in the study of municipal-level investment [PDF]
, 2017 In our research we specially adapted the multiplier accelerator approach for analysis of investment processes on the municipal level. We analyzed the databases of municipalities of the Bashkortostan Republic and found a one-year lag and ratchet effects ...
Kazakova, O. B., Kuzminykh, N. A.
core +3 more sources