Results 71 to 80 of about 3,574 (241)

Targeting Tex10 Overcomes Oxaliplatin Resistance by Competitively Disrupting the Non‐Canonical BAF Complex in Colorectal Cancer

Advanced Science, EarlyView.
This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu, Jie Huang, Xiaojin Gao, Lin Deng, Yanheng Deng, Denglu Wang, Chunlei Yu, Yunxiang Zhang, Jingdong Li, Xiaocong Xiang   +9 more
wiley   +1 more source

Croissance économique des pays émergents et géographie mondiale des pierres précieuses

EchoGéo, 2011
Extraction activities evolution is more and more dependent on the increase of demand in the emerging countries. The consequences of this growth on the gemstone mining activities are complex.
Remy Canavesio
doaj   +1 more source

Incorporation and substitution of ions and H₂O in the structure of beryl [PDF]

European Journal of Mineralogy
Incorporation of ions into the crystal structure of beryl (Be3Al2[Si6O18]) can take place by direct ion-to-ion substitution of the framework components Al3+, Be2+ and Si4+ or by occupation of interstitial or structural channel sites.
C. S. Hanser, C. S. Hanser, T. Häger, T. Häger, R. Botcharnikov, R. Botcharnikov   +5 more
doaj   +1 more source

Tumor‐Derived Exosomal circAP2B1 Induces M2 Macrophage Polarization by Enhancing Mitochondrial Homeostasis to Promote Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
ESCC‐derived exosomal circAP2B1 promotes tumor progression by reprogramming mitochondrial metabolism via the ESRRA/KPNA1/MFN2 axis to induce M2 polarization of macrophages. ABSTRACT Esophageal squamous cell carcinoma (ESCC) remodels the immunosuppressive tumor microenvironment via exosome‐mediated intercellular communication.
Yiru Wang, Gang Feng, Youyu Wang, Ruihao Liang, Haixia Pan, Kai Lei   +5 more
wiley   +1 more source

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

Advanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi, Lin Yang, Kang‐Li Wang, Hui‐Zhu Liu, Rui‐Ying Chen, Min Su, Xiao Xiao, Yu‐Qiu Zhang   +7 more
wiley   +1 more source

Eugene Werner Setting a Gemstone (S2_B3_F3_58)

, 2020
Department of Art.
University of Akron
core   +1 more source

Ergonomic design and evaluation of gemstone polishing workstation

, 2022
Objectives. Gemstone polishers suffer from musculoskeletal problems due to constrained working postures, substantially influenced by the poor design of conventional gemstone polishing workstations.
Dipayan Das (13870279), Ashish Kumar Singh (206583)   +1 more
core   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

PENGARUH MAJALAH INDONESIA GEMSTONE TERHADAP OPINI PUBLIK TENTANG BATU AKIK

, 2015
Abstrak Demam batu akik di Indonesia tidak terlepas dari banjirnya permintaan hingga ke mancanegara. Warga mulai berburu dan beralih menjadi penambang batu akik karena berharap bisa mendulang keuntungan, majalah IGS adalah sumber informasi batu akik ...
Adnan, Iis Zilfah, Eka Putra, Dadang Andika   +1 more
core   +1 more source

KOSAKATA BATU DALAM BAHASA-BAHASA DAERAH DI INDONESIA: ANALISIS LINGUISTIK BANDINGAN HISTORIS

CaLLs: Journal of Culture, Arts, Literature, and Linguistics, 2017
The phenomenon of gemstone or in Indonesia known as “batu akik” happened greatly in the early to the middle of 2015 and has become attention among the people in Indonesia. Although it cannot be identified precisely when the phenomenon of people massively
Syamsul Rijal
doaj   +1 more source