Results 201 to 210 of about 10,184 (280)

Flexible white thermally activated delayed fluorescence polymer with alkyl spacer and side‐chain encapsulation for efficient solution‐processed white organic light‐emitting diodes

FlexMat, EarlyView.
A “gemstone‐necklace” FASCE strategy synthesizes single‐component white polymers (PTF‐Qx) by alternating rigid TADF units with flexible alkyl chains. The non‐doped rigid device achieves a high EQE of 15.66% with stable white emission (CIE: 0.36, 0.46).
Wenhao Zhang, Hongyu Zhuang, Xinxin Ban, Shilong Feng, Tao Xu, Youqiang Qian, Shun Hu, Aiyun Zhu   +7 more
wiley   +1 more source

Dual-energy computed tomography iodine maps for visualizing enhancement and estimating characteristics in plaques. [PDF]

Radiol Case Rep
Maruyama M, Shota H, Aso H, Araki H, Yoshida R, Ando S, Nakamura M, Yoshizako T, Nihara H, Yamasaki O, Kaji Y.   +10 more
europepmc   +1 more source

Efficacy and immunogenic effects of Tumor Treating Fields (TTFields) in preclinical models of pancreatic ductal adenocarcinoma, with and without gemcitabine/nab‐paclitaxel

International Journal of Cancer, EarlyView.
What's New? Adaptive immune responses are typically limited in pancreatic ductal adenocarcinoma, resulting in minimal efficacy of immune checkpoint inhibitors. Tumor Treating Fields (TTFields) therapy, which uses low‐intensity intermediate‐frequency electric fields to disrupt cancer cell processes, has been approved for certain cancers.
Tal Kan, Tharwat Haj Khalil, Yiftah Barsheshet, Tali Voloshin, Lilach Koren, Bella Koltun, Cfir David, Kerem Wainer‐Katsir, Avital Vorontsova, Boris Brant, Simona Zisman‐Rozen, Hila M. Ene, Roni Frechtel‐Gerzi, Shay Cahal, Anat Klein‐Goldberg, Lena Lifshitz, Efrat Zemer Tov, Mai Shai, Adi Haber, Moshe Giladi, Uri Weinberg, Yoram Palti   +21 more
wiley   +1 more source

Holistic bone developing microenvironment engineered apoptotic extracellular vesicles recapitulate multidimensional developmental signatures in adult and senile bone repair

Interdisciplinary Medicine, EarlyView.
The developing bone was identified as an M2a‐like macrophage driven immune microenvironment with multidimensional developmental signatures. hME‐ApoEVs were successfully fabricated via stimulating the M2a‐like developing microenvironment in vitro and confirmed its recapitulation of developmental features.
Xiaoran Yu, Jieyun Xu, Yuan Zhao, Xinyu Guo, Hongcheng Chen, Junlong Xue, Yong Ao, Linjun Zhang, Xiaomeng Gao, Xueli Mao, Songtao Shi, Zetao Chen   +11 more
wiley   +1 more source

First-Line Sugemalimab Plus Chemotherapy for Advanced Gastric Cancer: The GEMSTONE-303 Randomized Clinical Trial.

JAMA
Zhang X, Wang J, Wang G, Zhang Y, Fan Q, Lu C, Hu C, Sun M, Wan Y, Sun S, Wang J, Zhang L, Shu Y, Luo J, Zhu D, Shen Z, Yao S, Shi Q, Yang J, Shen L, GEMSTONE-303 Investigators.   +20 more
europepmc   +1 more source

Efficacy and Safety of Anti-PD-(L)1 Treatments: A Systematic Review and Meta-Analysis of Asian vs Non-Asian Patients with Esophageal Squamous Cell Carcinoma. [PDF]

Gastro Hep Adv
Ajani J, Zhan L, Kadva A, Kato K, Kretz J, Pietrantonio F, Kelly RJ, Zhang X, Lorenzen S.   +8 more
europepmc   +1 more source

Monocytes with trained immunity–like signatures are associated with acute anterior uveitis in ankylosing spondylitis

Interdisciplinary Medicine, EarlyView.
In ankylosing spondylitis‐acute anterior uveitis (AS‐AAU), trained immunity monocytes (Mono‐TI) differentiate into macrophages in the eye, retaining trained immunity features. Mono‐TI cells secrete pro‐inflammatory cytokines and chemokines, including IL‐1β, TNF‐α, and CCL3.
Yimeng Sun, Lu Zhang, Xinyu Yao, Yunfei Liu, Xin Li, Feng Wen, Yong Dai, Ye Dai, Ziyu Du, Dijie Qiao, Ziwei Meng, Cong Hu, Chun Yan, Wei Chi   +13 more
wiley   +1 more source

Utility of an artificial intelligence-based lung CT airway model in the quantitative evaluation of large and small airway lesions in patients with chronic obstructive pulmonary disease. [PDF]

BMC Pulm Med
Liu Z, Li J, Li B, Yi G, Pang S, Zhang R, Li P, Yin Z, Zhang J, Lv B, Yan J, Ma J.   +11 more
europepmc   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Does chemotherapy regimen matter for first-line immunochemotherapy in low PD-L1-expressing esophageal squamous cell carcinoma? A systemic review and meta-analysis. [PDF]

Esophagus
Guo JC, Lin PS, Shau WY, Shao YY, Kuo HY, Chen CL, Hsu CH.   +6 more
europepmc   +1 more source