Results 1 to 10 of about 11,477 (124)

Colorectal cancer biomarkers and their impact on the clinical practice

open access: yesBrazilian Journal of Oncology, 2021
Colorectal cancer (CRC) holds third place in the global ranking of malignancies worldwide. Patients with CRC commonly show distinct outcomes and treatment responses due to their biological features and tumoral biomarkers.
James Crespo   +4 more
doaj   +1 more source

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

open access: yesHepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández   +18 more
wiley   +1 more source

Downregulation of FeSOD-A expression in Leishmania infantum alters trivalent antimony and miltefosine susceptibility

open access: yesParasites & Vectors, 2021
Background Superoxide dismutase (SOD), a central component of the antioxidant defence system of most organisms, removes excess superoxide anions by converting them to oxygen and hydrogen peroxide. As iron (Fe) SOD is absent in the human host, this enzyme
Ana Maria Murta Santi   +3 more
doaj   +1 more source

M. bovis BCG Moreau N-Terminal Loss Leads to a Less Stable Dodecin With Lower Flavin Binding Capacity

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Tuberculosis still remains a concerning health problem worldwide. Its etiologic agent, Mycobacterium tuberculosis, continues to be the focus of research to unravel new prophylactic and therapeutic strategies against this disease.
Marcos Gustavo Araujo Schwarz   +6 more
doaj   +1 more source

Biorrevelações: testes de ancestralidade genética em perspectiva antropológica comparada

open access: yesHorizontes Antropológicos, 2011
É cada vez maior o número de empresas que comercializam testes de ancestralidade genética a partir do DNA, sobretudo, na América do Norte. Tal fenômeno tem atraído a atenção das ciências sociais, em particular da antropologia.
Verlan Valle Gaspar Neto   +1 more
doaj   +1 more source

Transcriptomic analysis of benznidazole-resistant and susceptible Trypanosoma cruzi populations

open access: yesParasites & Vectors, 2023
Background Chagas disease (CD), caused by the parasite Trypanosoma cruzi, is a serious public health concern in Latin America. Nifurtimox and benznidazole (BZ), the only two drugs currently approved for the treatment of CD, have very low efficacies in ...
Davi Alvarenga Lima   +6 more
doaj   +1 more source

Brief history of Eucalyptus breeding in Brazil under perspective of biometric advances

open access: yesCiência Rural, 2016
: Forest breeding is a science that has been developing in Brazil since 1941 being the Eucalyptus a highlighted genus in this scenario. In a global scene, Brazil is displayed prominently in productivity of Eucalyptus planting, due to favorable ...
Carla Aparecida de Oliveira Castro   +3 more
doaj   +1 more source

Resistome in Lake Bolonha, Brazilian Amazon: Identification of Genes Related to Resistance to Broad-Spectrum Antibiotics

open access: yesFrontiers in Microbiology, 2020
Resistance to antibiotics is one of the most relevant public health concerns in the world. Aquatic environments play an important role because they are reservoirs for antibiotic resistance genes and antibiotic-resistant strains, contributing to the ...
Jorianne Alves   +10 more
doaj   +1 more source

Advances in apple culture worldwide

open access: yesRevista Brasileira de Fruticultura, 2011
Over the last 60 years, planting densities for apple have increased as improved management systems have been developed. Dwarfing rootstocks have been the key to the dramatic changes in tree size, spacing and early production.
Terence Robinson
doaj   +1 more source

Tamanho de população ideal para mapeamento genético em famílias de irmãos completos Optimum population size for genetic mapping in full sibling families

open access: yesPesquisa Agropecuária Brasileira, 2008
O objetivo deste trabalho foi avaliar o tamanho ótimo de populações de irmãos completos, para estudos de mapas de marcadores moleculares, por meio de simulações de genomas e tamanhos de populações.
Leonardo Lopes Bhering   +1 more
doaj   +1 more source

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