Results 51 to 60 of about 11,477 (124)
Journal of the Science of Food and Agriculture, Volume 106, Issue 10, Page 5841-5850, 15 August 2026.Abstract BACKGROUND Fungus‐resistant PIWI (Pilzwiderstandsfähig) grape cultivars are promising for reducing pesticide inputs in viticulture, but their enological potential is still poorly characterized. We performed a pilot, single‐vintage study integrating berry gene expression and phenolic composition in five Italian red PIWI cultivars (Cabernet ...
Clizia Villano +8 more
wiley +1 more source
ChemBioChem, Volume 27, Issue 15, 14 August 2026.Organometallic derivatization of existing drugs is a common strategy to look for new drug candidates. This work describes the derivatization of the benzimidazole anthelmintic scaffold, from the synthesis of the organometallic derivatives to the evaluation of their biological properties. It highlights a broad range of antiparasitic activities and leaves
Corentin Ludwig +14 more
wiley +1 more source
A computational framework for extracting biological insights from SRA cancer data
Scientific ReportsThe integration of sequenced samples and clinical data from independent yet related studies from public domain databases, such as The Sequence Read Archive (SRA), has the potential to increase sample sizes and enhance the statistical power needed for ...
Paul Anderson Souza Guimarães +2 more
doaj +1 more source
Comparative transcriptomic analysis of antimony resistant and susceptible Leishmania infantum lines
Parasites & Vectors, 2020 Background One of the major challenges to leishmaniasis treatment is the emergence of parasites resistant to antimony. To study differentially expressed genes associated with drug resistance, we performed a comparative transcriptomic analysis between ...
Juvana Moreira Andrade +13 more
doaj +1 more source
Aging Cell, Volume 25, Issue 8, August 2026.We demonstrated that progerin induces the formation of autophagosomes but impairs their maturation and subsequent fusion with lysosomes. Progerin impedes proper autophagy flux, thus preventing its own autophagic degradation. Selinexor treatment improved both autophagosome maturation and autophagosome‐lysosome fusion, which ultimately led to effective ...
Ian García‐Aguirre +18 more
wiley +1 more source
Scientific ReportsVisceral cestodiases, like cysticercoses and echinococcoses, are caused by cystic larvae from parasites of the Cestoda class and are endemic or hyperendemic in many areas of the world.
Renato Kulakowski Corá +3 more
doaj +1 more source
Organic acid effects on Brassica napus L. var. oleifera seed germination and seedling growth
Revista de Ciências Agroveterinárias, 2019 Canola (Brassica napus L. var. oleifera) is cultivated in the Southern Brazil as an alternative winter crop in the rotation system. No-tillage and hydromorphic soils favor the formation of aliphatic organic acids with short chain and low molecular weight,
Ana Marina Pedrolo +8 more
doaj +1 more source
Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.This work highlights the satisfactory pharmacokinetic profile of two benzenesulfonylpiperazine lead candidates, followed by in vivo assessment in a murine model of visceral leishmaniasis. This assessment identified compound 2 as moderately active at a lower dose, but its efficacy increased at higher doses, though with concerns regarding safety.
Thibault Joseph William Jacques Dit Lapierre +13 more
wiley +1 more source
Assessing differences among elasmobranch nurseries to aid conservation based on a genomics framework
Conservation Biology, Volume 40, Issue 4, August 2026.Abstract Elasmobranch nurseries often differ in environmental conditions, demographics, and use patterns. These differences affect the distribution of genetic variation among nurseries. However, conservation and management strategies often fail to account for such differences because they are difficult to characterize.
Dominic G. Swift +8 more
wiley +1 more source
A vida do livro e o livro da vida: escrita, leitura e biotecnologias
Fractal: Revista de PsicologiaRESUMO O presente artigo tem como objetivo analisar as tensões estabelecidas entre a linguagem e o poder em duas searas aparentemente distintas: a genômica e o livro.
Leonardo Pinto de Almeida +1 more
doaj +1 more source