Results 51 to 60 of about 17,352 (158)

Assessment of the scientific-technological production in molecular biology in Brazil (1996-2007): the contribution of genomics programs

open access: yesAnais da Academia Brasileira de Ciências, 2011
Several genome sequencing programs were launched in Brazil by the end of the nineties and the early 2000s.The most important initiatives were supported by the ONSA program (http://watson.fapesp.br/onsa/Genoma3.htm) and aimed at gaining domain in genomic ...
Rogério Meneghini, Estêvão C. Gamba
doaj  

Cell Surface Markers Identify Astrocyte Subpopulations in the Adult Hippocampus With a Heterogeneous Response to Aging

open access: yesGlia, Volume 74, Issue 11, November 2026.
ATP1B2 and GLAST identify two astrocyte subpopulations in the hippocampus with distinct molecular signatures. Transcriptomic shifts during aging differ between both subpopulations. Aged ATP1B2+ astrocytes rewire their metabolism while double‐positive aged astrocytes display a reduced synaptogenic capability.
Lucía Casares‐Crespo   +6 more
wiley   +1 more source

Seleção genômica ampla e novos métodos de melhoramento do milho [PDF]

open access: yes, 2012
Os objetivos deste trabalho foram verificar a acurácia do método da Seleção Genômica Ampla (GWS) no melhoramento de milho nas condições de estresse nutricional e propor novos métodos de melhoramento baseados em GWS. Foram estimados os dois componentes da
Fritsche-Neto, Roberto   +7 more
core   +1 more source

The MexMAGIC population reveals the genetic architecture of traits exhibiting clinal variation in Mexican native maize

open access: yesNew Phytologist, Volume 252, Issue 3, Page 1296-1313, November 2026.
The MexMAGIC population mixes native maize varieties from across Mexico to study functional genetic diversity. Summary Defining the genetic basis of local adaptation is a key goal of evolutionary biology and crop improvement. Theory predicts that when selective pressures follow differences in the environment, a cline will be established.
Sergio Perez‐Limón   +18 more
wiley   +1 more source

Proteômica comparativa aplicada à cultura de tecidos de plantas

open access: yesOrnamental Horticulture, 2007
Nas últimas décadas os códigos genéticos de diversos organismos foram completamente seqüenciados, representando um importante avanço do conhecimento na área genômica. No contexto das “ômicas” grande ênfase tem-se dado para a genômica funcional, que visa
Leonardo L. C. Dias   +3 more
doaj   +1 more source

A Novel KCNA1 Variant in a Patient With Tremor and Autism Spectrum Disorder Causes Mixed LOF/GOF Defects of Kv1.1 Channels

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 10, Page 2166-2171, October 2026.
ABSTRACT Variants in KCNA1, encoding the Kv1.1 potassium channel, cause neurological disorders including episodic ataxia and developmental and epileptic encephalopathy. We identified a novel KCNA1 variant (A401T) in a 16‐year‐old patient with autism spectrum disorder, borderline intellectual disability, and tremor, without episodic ataxia or epilepsy ...
Juan Darío Ortigoza‐Escobar   +7 more
wiley   +1 more source

ENFERMAGEM EM GENÔMICA: O ACONSELHAMENTO GENÉTICO NAS PRÁTICAS ASSISTENCIAIS [PDF]

open access: yes, 2017
RESUMO O presente artigo tem como objetivo refletir sobre a atuação do enfermeiro na área da genômica, no contexto atual da saúde, com ênfase no papel de conselheiro genético.
Dirceu Antônio Cordeiro   +1 more
core   +1 more source

Genetic Risk and High Burden of Depression and Suicide in the Maya‐Mestizo Population of Yucatán, México

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 7, Page 431-440, October 2026.
ABSTRACT Major depression and suicide are critical public health concerns, particularly in underrepresented populations with unique genetic and sociocultural contexts. The Maya‐mestizo population presents the highest suicide rates in the country but remains understudied in psychiatric genetics. This study evaluated the association between three genetic
Marta Menjivar   +3 more
wiley   +1 more source

miRNAs as Diagnostic and Prognostic Biomarkers in Pancreatic Ductal Adenocarcinoma and Its Precursor Lesions: A Review

open access: yesBiomarker Insights, 2015
Pancreatic ductal adenocarcinoma (PDAC), a rare but lethal tumor, is difficult to diagnose without performing an invasive procedure. miRNAs are known to be deregulated in PDAC patients, and recent studies have shown that they can be used as diagnostic ...
Bárbara Alemar   +2 more
doaj   +1 more source

Molecular evolution of toothed whale genes reveals adaptations to echolocating in different environments

open access: yesBMC Genomics
Background Echolocation was a key development in toothed whale evolution, enabling their adaptation and diversification across various environments. Previous bioacoustic and morphological studies suggest that environmental pressures have influenced the ...
L. Magpali   +4 more
doaj   +1 more source

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