Results 91 to 100 of about 773,997 (285)

Gender-based violence and efforts to address the phenomenon: Towards a church public pastoral care intervention proposition for community development in Zimbabwe

HTS Teologiese Studies/Theological Studies, 2019
Gender-based Violence (GBV) is a huge concern in many African countries such as Zimbabwe despite the preventative and mitigatory interventions that have been proposed and implemented by various stakeholders.
Vhumani Magezi, Peter Manzanga
doaj   +1 more source

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

Advanced Science, EarlyView.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng, Hongyong Song, Yin Long, Kaimin Wu, Yinkun Fu, Wenkai Zhou, Wenyan Li, Zhe Shi, Xu‐Yun Zhao   +8 more
wiley   +1 more source

Press coverage of same-sex domestic violence cases in Spain [PDF]

, 2016
Introduction. Spanish media have covered several cases of violence in same-sex couples in recent years. Reporting on this phenomenon raises questions about how to approach a reality that had remained hidden until recently. Method. The aim of this article
Carratalá Simón, Adolfo
core   +2 more sources

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source

Sex Trafficking of Minors in New York: Increasing Prevention and Collective Action [PDF]

, 2012
The Foundation's funding in Anti-Violence and Safety has helped us to better understand the issues and challenges of poverty and gender-based violence that women and girls have had to overcome.
Elizabeth Hines, Joan Hochman
core  

Violencia de género : reflexiones conceptuales, derivaciones prácticas [PDF]

, 2007
El objetivo de este artículo es analizar el término violencia de género, destacando sus características y potencialidades, tanto teóricas como prácticas.
Espinar Ruiz, Eva, Mateo Pérez, Miguel Ángel   +1 more
core   +4 more sources

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

The Zero Violence Brave Club: a successful educational action to overcome isolating gender-based violence with young adolescents

Journal of New Approaches in Educational Research
Some programs and actions contribute to the reduction of violence in schools, but the relevance of studying isolating gender-based violence for overcoming school-related gender-based violence has not been analyzed.
Sara Carbonell Sevilla, Patricia Melgar Alcantud, Oriol Ríos González, Itxaso Tellado Ruiz de Gauna, Josep Maria Canal Barbany   +4 more
doaj   +1 more source

Optimizing Legal Protection against Gender-Based Violence From an Islamic Perspective

Al-Izzah
Gender-based violence in Indonesia is increasingly concerning, despite the existence of numerous laws and regulations aimed at its regulation. This violence significantly impedes development, as its multifaceted impact hinders women's participation ...
Nur Saniah, Marlina Marlina, Lia Agustina Damanik   +2 more
doaj   +1 more source

NQO1‐Mediated Anoikis Resistance and Immune Evasion Define a High‐Risk Multi‐Omic Subtype for Precision Management of T1 High‐Grade Bladder Cancer

Advanced Science, EarlyView.
Multi‐omic profiling of T1 high‐grade bladder cancer identifies a high‐risk subtype (T1HG1) driven by NQO1, which couples anoikis resistance with immune evasion. NQO1 orchestrates macrophage–T cell crosstalk suppression via CXCL9 modulation. Pharmacological NQO1 inhibition with skullcapflavone II enhances cisplatin efficacy, representing a promising ...
Bin Guo, Chunru Xu, Shufan Fu, Qiang Cheng, Juan Li, Linkuo Shang, Gaojie Li, Yang Yang, Ying Wang, Yanqing Gong, Shengwei Xiong, Jian Fan, Changwei Yuan, Mei Zhang, Yifan Zuo, Elena Papaleo, Yue Shi, Yuan Liang, Xuesong Li, Hongzhao Li, Weimin Ci   +20 more
wiley   +1 more source