Results 81 to 90 of about 773,997 (285)

Concept and Representation of Gender-based Violence: Reflections about the Impact on Young People [PDF]

, 2015
Recent studies and reports reveal that young people have a distorted concept of gender-based violence and their tolerance towards it does not decrease. There is a context of institutional concern about prevention and eradication of gender-based violence ...
Campos Mansilla, Beatriz, Liberia Vayá, Irene, Zurbano-Berenguer, Belén   +2 more
core  

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Understanding the nature and etiology of intimate partner violence and [PDF]

, 2011
Theoretical perspectives underlying hypotheses about the nature and etiology of intimate partner violence are important as they inform professionals how they should best respond to reduce or eliminate this social problem.
Dixon, Louise
core  

Honour based violence as a global public health problem: a critical review of literature [PDF]

, 2016
Purpose : 'Honour' Based Violence (HBV), a form of Gender Based Violence (GBV), has received increasing interest from media, human rights organisations, academics and public.
Bhanbhro, Sadiq, Cronin De Chavez, Anna, Lusambili, Adelaide   +2 more
core   +1 more source

ZSL Orchestrates Synaptonemal Complex Assembly as a Central Region Scaffold to Ensure Synapsis Fidelity and Crossover Control in Polyploid Meiosis

Advanced Science, EarlyView.
A central molecular adaptor, ZSL, is identified that links transverse filaments ZYP1 to central element SCEP1/2 to drive synaptonemal complex assembly in Brassica napus. Loss of ZSL abolishes synaptonemal complex formation, disrupts meiotic chromosome segregation, and markedly increases crossovers, providing mechanistic insight into meiotic fidelity ...
Miaowei Geng, Shaochen Jia, Fei Cao, Cuiping Liu, Heshuang Zhang, Gang Xu, Jixin Zhuang, Yashi Zhang, Can Liu, Yuhang Zhao, Zilin Guo, Xinjie Yuan, Jiaqing Yang, Lei Chu, Bowei Cai, Hu Zhao, Chao Yang   +16 more
wiley   +1 more source

Conceptualizing sexual and gender-based violence in European asylum reception centers [PDF]

, 2019
Background: Sexual and gender based violence (SGBV) is a major public health problem and a violation of human rights. Refugees, asylum seekers and migrants are exposed to a constant risk for both victimization and perpetration.
Dias, Sónia, Keygnaert, Ines, Neves de Oliveira, Charlotte, Oliveira Martins, Maria do Rosário   +3 more
core   +2 more sources

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Gender-based violence and reproductive health in five Indian states [PDF]

, 2012
Gender-based violence is a multi-faceted public health problem with numerous consequences for an individual’s physical and mental health and wellbeing. This collection develops a comprehensive public health approach for working with gender-based violence,
Coast, Ernestina, Leone, Tiziana, Malviya, Alankar   +2 more
core  

Sexual violence in Iraq: Challenges for transnational feminist politics [PDF]

, 2016
The article discusses sexual violence by ISIS against women in Iraq, particularly Yezidi women, against the historical background of broader sexual and gender-based violence.
Al-Ali N, Al-Ali N, Begikhani N, Cockburn C, Cockburn C, Cockburn C, Efrati N, Enloe C, Enloe C, Enloe C, Hardi C, Kanie M, Mojab S, Mojab S, Nadje Al-Ali, Omar S, Rohde A, Russell B, Wibben A, Wibben A   +19 more
core   +1 more source

POU2F1 Promotes Chemoresistance in Colorectal Cancer Cells via Attenuates the MDR2 Degradation Mediated by PPP1R11 Lactylation

Advanced Science, EarlyView.
Schematic diagram of our study showing that highly expressed POU2F1 in colorectal cancer (CRC) can directly accelerate the cytosolic lactate export to decrease PPP1R11 lactylation at K59, thereby attenuating the E3 ligase enzyme activity and protein stability of PPP1R11, which inhibits the ubiquitination of MDR2 at K413 and K538 but increases the ...
Longzheng Xia, Jinguan Lin, Xianjie Jiang, Linda Oyang, Shiming Tan, Zongyao Ren, Qiu Peng, Qianjin Liao, Yujuan Zhou   +8 more
wiley   +1 more source