Results 31 to 40 of about 770,818 (335)

Women in Gender (Critical Discourse Analysis on Novel I Am Malala by Malala Yousafzai and Christina Lamb) [PDF]

open access: yes, 2016
The purpose of this study was to describe how the text of gender-based violence against the woman, and illustrate how gender-based injustice is run and produced in the Novel I am Malala, through the texts that have been written.
Syamsiah, N. (Nur)
core   +3 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

School Actions to Prevent Gender-Based Violence: A (Quasi-)Systematic Review of the Brazilian and the International Scientific Literature

open access: yesFrontiers in Education, 2018
The study aimed to provide scientific evidence to support school actions for the prevention of gender-based violence (GBV), specifically in the Brazilian context. Brazil presents high GBV indexes, ranking fifth in the world in femicide.
Bruno C. Prezenszky   +3 more
doaj   +1 more source

Efforts to Address Gender-Based Violence: A Look at Foundation Funding [PDF]

open access: yes, 2010
Gender-based violence is one of the most insidious and pervasive problems affecting women. Throughout the world, it is estimated that one in three will be raped, beaten, coerced into sex or otherwise abused in her lifetime.While foundation support of ...

core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Conceptualizing sexual and gender-based violence in European asylum reception centers [PDF]

open access: yes, 2019
Background: Sexual and gender based violence (SGBV) is a major public health problem and a violation of human rights. Refugees, asylum seekers and migrants are exposed to a constant risk for both victimization and perpetration.
Dias, Sónia   +3 more
core   +2 more sources

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

Psychosocial effects of gender-based violence among women in Vhembe district: A qualitative study

open access: yesSouth African Journal of Psychiatry, 2023
Background: The phenomenon of gender-based violence is a pertinent social problem in South Africa. The fear of reporting gender-based violence contributes to its continuation, marginalisation and silencing of victims.
Rodney Rikhotso   +2 more
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

The ethics of knowledge sharing: a feminist examination of intellectual property rights and open-source materials in gender transformative methodologies

open access: yesFrontiers in Research Metrics and Analytics
Debates on intellectual property rights and open source frequently stem from the business sector and higher education, where goals are typically oriented toward profit, academic status, credit, and/or reputation.
Leah Goldmann   +10 more
doaj   +1 more source

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