Results 51 to 60 of about 24,294,651 (284)

De/gendering violence and racialising blame in Swedish child welfare : what has childhood got to do with it?

open access: yes, 2021
This article is a critical interrogation of how gender and power figure in Swedish child welfare policy and the discourses on violence in intimate relationships vis-à-vis children exposed to violence.
Eriksson, Maria   +5 more
core   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

open access: yesAdvanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai   +9 more
wiley   +1 more source

Gender-Based Violence: How South Sudan is fighting back

open access: yes, 2023
From the first Sudanese civil war in 1955 to cyclical conflicts post-independence, the scarlet cord of violence is inextricably woven into the history of South Sudan.
Nyakomi Adwok
core   +1 more source

LRRC4 Orchestrates AP2A1‐Containing Clathrin‐Coated Vesicles to Disrupt Mitochondrial Cristae and Restrict Glioblastoma Progression

open access: yesAdvanced Science, EarlyView.
LRRC4 suppresses GBM by regulating AP2A1‐containing Golgi‐derived clathrin‐coated vesicles. Low LRRC4 allows cytoplasmic AP2A1 to maintain mitochondrial fission‐fusion, MICOS integrity, and OXPHOS, promoting proliferation and invasion. High LRRC4 redirects AP2A1‐containing Golgi‐derived clathrin‐coated vesicles to mitochondria, disrupts MICOS, enhances
Yang Li   +5 more
wiley   +1 more source

Riconoscere la violenza: dai modelli culturali e sociali ai limiti della presa in carico / Reconnaître la violence : modèles culturels et sociaux et limites de la prise en charge / Recognising violence : from cultural and social models to the limits of care and support [PDF]

open access: yesRivista di Criminologia, Vittimologia e Sicurezza, 2013
Gli autori descrivono un’esperienza clinica, nella prospettiva psicoanalitica, relativa alla violenza sulle donne. In particolare, gli autori ipotizzano che la percentuale massiccia di mancata denuncia da parte delle donne delle violenze subite, sia ...
Stanziano Giuseppe   +1 more
doaj  

Histone H3K18 Lactylation Promotes the Malignant Progression of Wilms Tumor via a PSRC1/AKT/HIF‐1α Positive Feedback Loop

open access: yesAdvanced Science, EarlyView.
In nephroblastoma, aberrant glycolysis drives lactate accumulation, which elevates histone H3K18 lactylation via p300. Lactylation of the PSRC1 promoter activates its transcription. PSRC1 competitively binds AKT, relieving PTEN‐mediated inhibition and triggering AKT/mTOR/HIF‐1α signaling.
Yanping Wang   +6 more
wiley   +1 more source

CA9‐Targeted PET Imaging for Noninvasive Discrimination of Clear Cell Renal Cell Carcinoma and Associated Tumor Biological Features

open access: yesAdvanced Science, EarlyView.
CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.
Kailei Chen   +19 more
wiley   +1 more source

Gender equality and violence against women: what’s the connection? [PDF]

open access: yes, 2014
A lack of gender equality is consistently cited as an underlying determinant of violence against women. The United Nations General Assembly, in its 1993 Declaration on the Elimination of Violence Against Women, noted that this violence is a manifestation
Liz Wall
core  

Experience‐Dependent Reorganization of Hippocampal CA3 Neuronal Ensembles Associates With Memory Generalization

open access: yesAdvanced Science, EarlyView.
Mice can transfer the learned rule of spatial working memory to guide similar but novel tasks. Hippocampal CA3 populational activity dynamically reorganize during memory generalization, shifting from task‐specific to generalized coding over testing days. Sparse yet redundant neural representations of CA3 enable rule transfer and cognitive map formation,
Da Song   +8 more
wiley   +1 more source

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