Results 61 to 70 of about 24,294,651 (284)

Understanding and addressing gender-based violence in Eswatini

International Review of Social Sciences Research
The high prevalence of gender-based violence (GBV) in the kingdom of Eswatini is quiet saddening. Women and girl children become victims of GBV to the extent of losing their lives.
Phumuzani Mpofu, Siphiwe Hlobsile Tfwala
doaj   +1 more source

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

Advanced Science, EarlyView.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon, Maria Tsiokou, Patricia Marqués, Enriqueta Rodríguez‐Diaz, Hazel Ang, Federico Pietrocola, Christian G. Riedel   +6 more
wiley   +1 more source

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

Advanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu, Qing Li, Yiyang Xu, Zitao Wang, Hua Shu, Yangfan Wu, Fang Lu, Zhimin Huang, Bo Zhang, Hongwei Liang, Changying Xing, Huijuan Mao, Yanggang Yuan   +12 more
wiley   +1 more source

SIKAP MASYARAKAT KUDUS TERHADAP UNDANG-UNDANG TENTANG PENGHAPUSAN KEKERASAN DALAM RUMAH TANGGA

Muwazah, 2012
This study is about PKDRT law. It gives us information that domestic violence is a real thing that happens in our society, especially in Kudus. On the one hand, civil society actually has a formula to prevent the authority and rights of their family life
Anisa Listiana dan M. Widjanarko
doaj   +1 more source

Discourse analysis of gender-based violence in contemporary Kiswahili fiction: A case study of selected novels of the past three decades (1975 - 2004) and young Tanzanians’ interpretations [PDF]

, 2013
This study focused on indirect exposure to violence against women by examining the discursive construction of gender-based violence in Kiswahili novels.
Mosha, Ernesta Simon
core  

Preaching to the choir: effects of the Mentors in Violence Prevention programme on ‘the bad apples’

, 2023
Mentors in Violence Prevention (MVP) is a systematic education programme aimed at addressing gender inequality and preventing violence among boys and men. The programme originates from Canada and the USA, and since 2015 has been introduced in a number of
Joakim Billevik, Billevik, Joakim,, Daniel Lindberg, Lindberg, Daniel,   +3 more
core   +1 more source

Tumor‐Derived Exosomal circAP2B1 Induces M2 Macrophage Polarization by Enhancing Mitochondrial Homeostasis to Promote Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
ESCC‐derived exosomal circAP2B1 promotes tumor progression by reprogramming mitochondrial metabolism via the ESRRA/KPNA1/MFN2 axis to induce M2 polarization of macrophages. ABSTRACT Esophageal squamous cell carcinoma (ESCC) remodels the immunosuppressive tumor microenvironment via exosome‐mediated intercellular communication.
Yiru Wang, Gang Feng, Youyu Wang, Ruihao Liang, Haixia Pan, Kai Lei   +5 more
wiley   +1 more source

“I have learned that nothing is given for free”: an exploratory qualitative evaluation of a social norms edutainment intervention broadcast on local radio to prevent age-disparate transactional sex in Kigoma, Tanzania

BMC Public Health
Background Promising evidence supports the effectiveness of edutainment interventions in shifting norms to prevent violence against women and girls and other harmful practices, yet further research into mechanisms and pathways of impact is needed to ...
Lottie Howard-Merrill, Marjorie Pichon, Alice Witt, Revocatus Sono, Veronicah Gimunta, Enrica Hofer, Fatina Kiluvia, Mengi Alfred, Emmanuel Yohanna, Ana Maria Buller   +9 more
doaj   +1 more source

Asymmetric Evolution of Antennal Cell Types Underlies a Derived Ammonia‐Sensing Logic for Ecological Adaptation in Bactrocera dorsalis

Advanced Science, EarlyView.
Comparative antennal single‐nucleus transcriptomics reveals cell‐type‐dependent transcriptomic divergence in Bactrocera dorsalis, with similar structural cells but divergent sensory neurons. This neuronal diversification is associated with a distinct ammonia‐sensing pathway, linking female attraction to bird‐dropping‐associated cues with nutritional ...
Wei Liu, Shuai Zhang, Jie Zhang, Zhen Tian, Yuanbo Xue, Ling Yang, Jun Xu, Guirong Wang   +7 more
wiley   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source