Results 81 to 90 of about 3,654,018 (269)

Problematization of Gender Identity in the Social Interactions of Transgender Individuals in Tehran [PDF]

open access: yesمسائل اجتماعی ایران
In Iran, despite the legal recognition of gender reassignment, transgender individuals continue to encounter profound cultural, social, and structural constraints.
Seyed Ali Hashemian Far, Sahar Heidari
doaj  

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

open access: yesAdvanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai   +9 more
wiley   +1 more source

The Gender and Security Agenda

open access: yes, 2020
This book examines the gender dimensions of a wide array of national and international security challenges. The volume examines gender dynamics in ten issue areas in both the traditional and human security sub-fields: armed conflict, post-conflict ...

core   +1 more source

LRRC4 Orchestrates AP2A1‐Containing Clathrin‐Coated Vesicles to Disrupt Mitochondrial Cristae and Restrict Glioblastoma Progression

open access: yesAdvanced Science, EarlyView.
LRRC4 suppresses GBM by regulating AP2A1‐containing Golgi‐derived clathrin‐coated vesicles. Low LRRC4 allows cytoplasmic AP2A1 to maintain mitochondrial fission‐fusion, MICOS integrity, and OXPHOS, promoting proliferation and invasion. High LRRC4 redirects AP2A1‐containing Golgi‐derived clathrin‐coated vesicles to mitochondria, disrupts MICOS, enhances
Yang Li   +5 more
wiley   +1 more source

Models of Publicly Funded Gender Affirming Surgery

open access: yes
Thirty years ago (1994), a small group of trans1 people, general practitioners, and Queensland Health Officers met at the Brisbane Sexual Health Clinic in Adelaide Street Brisbane Queensland, to discuss the establishment of the first Gender Health ...
Bromdal, A.   +11 more
core   +1 more source

Gender dysphoria: Transsexualism and identity [PDF]

open access: yes, 1993
This thesis explores an extreme form of gender dysphoria: that experienced by transsexuals. The thesis focuses especially on issues concerning identity.
Dixon, Stephen Michael
core  

Cutting words: Priming self-objectification increases the intention to pursue cosmetic surgery [PDF]

open access: yes, 2013
We examined whether subtle exposure to sexually objectifying cues increases women’s intentions to have cosmetic surgery. Undergraduate women (N = 116) were randomly assigned to a condition in which they unscrambled sentences containing words associated ...
Robbie M. Sutton   +5 more
core   +1 more source

Histone H3K18 Lactylation Promotes the Malignant Progression of Wilms Tumor via a PSRC1/AKT/HIF‐1α Positive Feedback Loop

open access: yesAdvanced Science, EarlyView.
In nephroblastoma, aberrant glycolysis drives lactate accumulation, which elevates histone H3K18 lactylation via p300. Lactylation of the PSRC1 promoter activates its transcription. PSRC1 competitively binds AKT, relieving PTEN‐mediated inhibition and triggering AKT/mTOR/HIF‐1α signaling.
Yanping Wang   +6 more
wiley   +1 more source

''Sex Changes'? Paradigm Shifts in 'Sex' and 'Gender' Following the Gender Recognition Act?' [PDF]

open access: yes
Gender transformations are normatively understood as somatic, based on surgical reassignment, where the sexed body is aligned with the gender identity of the individual through genital surgery – hence the common lexicon \'sex change surgery\'. We suggest
Stephen Whittle, Lewis Turner
core  

CA9‐Targeted PET Imaging for Noninvasive Discrimination of Clear Cell Renal Cell Carcinoma and Associated Tumor Biological Features

open access: yesAdvanced Science, EarlyView.
CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.
Kailei Chen   +19 more
wiley   +1 more source

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