Results 71 to 80 of about 3,568,884 (345)

Examining Mental Health Differences Between Transgender, Gender Nonconforming, and Cisgender Young People in British Columbia [PDF]

open access: gold, 2021
Rachal Pattison   +5 more
openalex   +1 more source

How Gender Differences Affect Mental Health Outcomes [PDF]

open access: yes, 2017
This literature review will examine how mental health can be influenced by differences in gender, while being viewed through a sociological lens.
Fusco, Julianna
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Gender differences of cardiovascular risk

open access: yesРоссийский кардиологический журнал, 2019
Despite the many unresolved issues on gender characteristics of cardiovascular health, accumulated data allows to generalize global, national, ethnic, and social patterns.
E. B. Shapovalova   +2 more
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Gender differences in presbyopia

open access: yesCommunity Eye Health Journal, 2009
Presbyopia is the loss of lens accommodation with age that results in an inability to focus at near distances. It is receiving growing attention because of the recognition that good near vision is needed to accomplish a broad range of tasks, not only ...
Ilesh Patel, Sheila West
doaj  

Gender Differences in Pedestrians’ Traffic Behaviors in Iran: A Study from a Candidate Safe Community [PDF]

open access: diamond, 2021
Morteza Haghighi   +4 more
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Training in the implementation of sex and gender research policies: an evaluation of publicly available online courses

open access: yesBiology of Sex Differences
Background Recently implemented research policies requiring the inclusion of females and males have created an urgent need for effective training in how to account for sex, and in some cases gender, in biomedical studies. Methods Here, we evaluated three
Annika Gompers   +2 more
doaj   +1 more source

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