Results 31 to 40 of about 7,265 (259)

A Novel Compound Heterozygous Mutation of HSD17B3 Gene Identified in a Patient With 46,XY Difference of Sexual Development

open access: yesSexual Medicine, 2022
Introduction: Deficiency of the 17β-hydroxysteroid dehydrogenase type 3 (17 β-HSD3) is a rare autosomal recessive 46,XY Difference of sex development (DSD), resulting from pathogenetic variants in the HSD17B3 gene, which lead to absent or reduced ability
Carlotta Cocchetti, MD   +7 more
doaj   +1 more source

SHBG as a Marker of NAFLD and Metabolic Impairments in Women Referred for Oligomenorrhea and/or Hirsutism and in Women With Sexual Dysfunction

open access: yesFrontiers in Endocrinology, 2021
PCOS is one of the most common endocrine disorders and NAFLD is one of its most dangerous metabolic consequences. The diagnosis of NAFLD is not a practical task and the condition is at risk of being overlooked.
Vincenza Di Stasi   +13 more
doaj   +1 more source

Effects of common Gram-negative pathogens causing male genitourinary-tract infections on human sperm functions

open access: yesScientific Reports, 2021
Male genitourinary tract (MGT) bacterial infections are considered responsible for 15% of male infertility, but the mechanisms underlying decreased semen quality are poorly known. We evaluated in vitro the effect of strains of Gram-negative uropathogenic
Sara Marchiani   +11 more
doaj   +1 more source

Gender Incongruence and Timing of Puberty: A Population-Based Cohort Study [PDF]

open access: yes, 2022
OBJECTIVE: To study whether the timing of puberty in adolescents who reported gender incongruence (incongruence between birth-assigned sex and self-identified gender) was different from those adolescents who reported gender congruence.DESIGN: Population ...
Lunddorf, Lea L. H.   +13 more
core   +1 more source

Life experiences leading to the choice of surgery—A qualitative study exploring reasons behind the choice of undergoing gender affirmative surgery

open access: yesFrontiers in Sociology, 2023
ObjectiveGender dysphoria is frequently accompanied by physical dissatisfaction and body image issues. The primary objective of this study is to explore subjective experiences and perceptions among those who has undergone gender reassignment surgery, as ...
Lene Kjelkenes Bjørnson   +1 more
doaj   +1 more source

Implications of the Estrogen Receptor Coactivators SRC1 and SRC2 in the Biological Basis of Gender Incongruence. [PDF]

open access: yesSex Med, 2021
[Abstract] Introduction Brain sexual differentiation results from the effects of sex steroids on the developing brain. The presumptive route for brain masculinization is the direct induction of gene expression via activation of the estrogen receptors α ...
Ramírez KDV   +6 more
europepmc   +3 more sources

Psychopathology in adult transgender people

open access: yesEuropean Psychiatry, 2021
Transgender people represent a broad spectrum of individuals that transiently or persistently identify with a gender different from the one assigned at birth (APA, 2013).
G. Castellini, J. Ristori, T. Steensma
doaj   +1 more source

Is oxidative stress evaluated in viable human spermatozoa a marker of good semen quality?

open access: yesFrontiers in Endocrinology, 2022
BackgroundOxidative stress is defined as the unbalance between reactive oxygen species (ROS) production and antioxidant defences. Whereas low levels of ROS are necessary for physiological sperm functions, high levels impair fertility damaging membranes ...
Giulia Traini   +6 more
doaj   +1 more source

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