Here gelatinase‐responsive methoxypolyethyleneglycol–PVGLIG–polycaprolactone (mPEG–PVGLIG–PCL) nanoparticles’ loading verteporfin (N@VP) is developed, enhancing radiotherapy via X‐ray‐triggered singlet oxygen generation. Combined with 2 Gy (gray, a radiation dose unit) irradiation, N@VP achieves antitumor efficacy comparable to 8 Gy, and also promotes ...
Zhifan Zhang+16 more
wiley +1 more source
HISTORY AND STUDY OF GENDER STUDIES
This article will talk about how important the concept of gender, which is one of the current topical treatments, is to be promoted to the life of society and, in Uzbekistan, to ensure women's rights, to protect women from violence and oppression. The article covers the origins of the term gender, its use in social fields, and the differences between ...
openaire +1 more source
Neural Patterns of Social Pain in the Brain‐Wide Representations Across Social Contexts
Empathy arises from both physiological and social pain, yet their shared and context‐specific neural mechanisms remain unclear. Combining fMRI and multivariate pattern analysis, this study decodes overlapping empathy networks and distinct representations for social exclusion versus separation.
Xiaodong Zhang+11 more
wiley +1 more source
"Precision Medicine" and the Failed Search for Binary Brain Sex Differences to Address Gender Behavioral Health Disparities. [PDF]
Eliot L.
europepmc +1 more source
Material deprivation and leading causes of death by gender: evidence from a nationwide small area study [PDF]
Joan Benach
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ADAR1‐HNRNPL‐Mediated CircCANX Decline Promotes Autophagy in Chronic Obstructive Pulmonary Disease
ADAR1‐HNRNPL interaction‐repressed circCANX recruits P53 mRNA and UPF1 to assemble a complex in nuclear. This complex promotes P53 mRNA degradation through the NMD pathway, and finally reduces autophagy and stress granules formation to further regulate inflammation.
Ting‐Ting Chen+10 more
wiley +1 more source
Gender differences in seasonality of acute myocardial infarction admissions and mortality in a population-based study [PDF]
Victor Grech
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Semaphorin 3E–Plexin D1 Axis Drives Lung Fibrosis through ErbB2‐Mediated Fibroblast Activation
TGF‐β1 stimulation in fibroblasts leads to increased Furin expression, Furin‐mediated cleavage of P87‐Sema3E to P61‐Sema3E, which affects fibroblast function through the autocrine pathway, and the P61‐Sema3E‐PlexinD1 axis promotes fibroblast activation, proliferation and migration by affecting ErbB2 phosphorylation, which in turn activates the ErbB2 ...
Zhesong Deng+12 more
wiley +1 more source
Commentary: Gender differences in job satisfaction and work-life balance among Chinese physicians in tertiary public hospitals. [PDF]
Sreya B+3 more
europepmc +1 more source