Results 61 to 70 of about 3,178,804 (292)

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Volume 11, Issue 41: November 21, 2011 [PDF]

open access: yes, 2011
https://ecommons.luc.edu/wsgs_digest/1042/thumbnail ...
Women\u27s Studies & Gender Studies Program,
core  

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Volume 11, Issue 30: September 5, 2011 [PDF]

open access: yes, 2011
https://ecommons.luc.edu/wsgs_digest/1031/thumbnail ...
Women\u27s Studies & Gender Studies Program,
core  

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Volume 11, Issue 23: March 28, 2011 [PDF]

open access: yes, 2011
https://ecommons.luc.edu/wsgs_digest/1024/thumbnail ...
Women\u27s Studies & Gender Studies Program,
core  

Enriching gender in PER: A binary past and a complex future [PDF]

open access: yes, 2015
In this article, we draw on previous reports from physics, science education, and women's studies to propose a more nuanced treatment of gender in physics education research (PER). A growing body of PER examines gender differences in participation, performance, and attitudes toward physics. We have three critiques of this work: (1) it does not question
arxiv   +1 more source

Sex of household head and trends in uptake of sulfadoxine-pyrimethamine intermittent preventive treatment for malaria during pregnancy: insights from secondary data in sub-Saharan Africa

open access: yesDiscover Social Science and Health
Background Malaria in pregnancy remains a serious public health concern in sub-Saharan Africa. The household head as a primary decision-maker plays a major role in women's utilization of maternal health services.
Benjamin Kobina Kwansa   +4 more
doaj   +1 more source

EDUCATIONAL OUTCOMES OF SCHOOL FEEDING INTERVENTION: EVIDENCE FROM RURAL NORTHERN GHANA [PDF]

open access: yesRussian Journal of Agricultural and Socio-Economic Sciences, 2014
The study investigated how policy intervention could have significant impact on beneficiaries. Using quasi-experimental design, 360 pupils from participating and non-participating schools in a feeding program were selected from a rural setting ...
Oloruntoba Abayomi, Musah Bukari
doaj  

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

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