Results 111 to 120 of about 1,154,991 (281)

The Effect of Prenatal Valproate Exposure in Serotonin Transporter Knockout Rats On Anxiety and Cognition: A Gene*Environment Interaction Model of Autism Spectrum Disorder

, 2015
Autism Spectrum Disorder is a complex neurodevelopmental disorder which is often associated with increased anxiety and deficits in cognitive ability.
August, Caren L.
core   +2 more sources

roben: Robust Bayesian Variable Selection for Gene-Environment Interactions [PDF]

, 2020
Jie Ren, Fei Zhou, Xiaoxi Li, Cen Wu
openalex   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A discussion of gene–gene and gene–environment interactions and longitudinal genetic analysis of complex traits [PDF]

, 2012
Ruzong Fan, Paul S. Albert, Enrique F. Schisterman   +2 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

An agent-based simulation framework for complex systems [PDF]

, 2012
In this abstract we present a new approach to the simulation of complex systems as biological interaction networks, chemical reactions, ecosystems, etc.
Benso, Alfredo, Di Carlo, Stefano, Politano, Gianfranco Michele Maria, Savino, Alessandro, Ur Rehman, Hafeez   +4 more
core  

Effects of Gene-Environment Interaction on Obesity among Chinese Adults Born in the Early 1960s [PDF]

, 2021
Weiyan Gong, Hui Li, Chao Song, Yuan Fan, Yanning Ma, Zheng Chen, Rui Wang, Hongyun Fang, Ailing Liu   +8 more
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

The nature of human altruism [PDF]

Some of the most fundamental questions concerning our evolutionary origins, our social relations, and the organization of society are centred around issues of altruism and selfishness.
Ernst Fehr, Urs Fischbacher
core  

Gene-Environment Interaction: Definitions and Study Designs [PDF]

, 2008
Ruth Ottman, Ruth Ottman
openalex   +1 more source