Results 171 to 180 of about 7,356,147 (250)

Gene-gene Interaction Analyses for Atrial Fibrillation. [PDF]

Sci Rep, 2016
Lin H, Mueller-Nurasyid M, Smith AV, Arking DE, Barnard J, Bartz TM, Lunetta KL, Lohman K, Kleber ME, Lubitz SA, Geelhoed B, Trompet S, Niemeijer MN, Kacprowski T, Chasman DI, Klarin D, Sinner MF, Waldenberger M, Meitinger T, Harris TB, Launer LJ, Soliman EZ, Chen LY, Smith JD, Van Wagoner DR, Rotter JI, Psaty BM, Xie Z, Hendricks AE, Ding J, Delgado GE, Verweij N, van der Harst P, Macfarlane PW, Ford I, Hofman A, Uitterlinden A, Heeringa J, Franco OH, Kors JA, Weiss S, Völzke H, Rose LM, Natarajan P, Kathiresan S, Kääb S, Gudnason V, Alonso A, Chung MK, Heckbert SR, Benjamin EJ, Liu Y, März W, Rienstra M, Jukema JW, Stricker BH, Dörr M, Albert CM, Ellinor PT.   +58 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Letter to George, from Gene, Burnett, Wisconsin, January 26, 1862

An item in the George Woodard and Gene Smith letters ...
Woodard, George T., -1864, Smith, Gene E.   +1 more
core  

Gene-gene interaction network analysis of hepatocellular carcinoma using bioinformatic software. [PDF]

Oncol Lett, 2018
He JH, Han ZP, Wu PZ, Zou MX, Wang L, Lv YB, Zhou JB, Cao MR, Li YG.   +8 more
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Letter to Gene, Burnett, Wisconsin, from George, April 17, 1863

An item in the George Woodard and Gene Smith letters ...
Woodard, George T., -1864, Smith, Gene E.   +1 more
core  

A novel susceptibility locus in MST1 and gene-gene interaction network for Crohn's disease in the Chinese population. [PDF]

J Cell Mol Med, 2018
Wu WKK, Sun R, Zuo T, Tian Y, Zeng Z, Ho J, Ho J, Wu JCY, Chan FKL, Chan MTV, Yu J, Sung JJY, Wong SH, Wang MH, Ng SC.   +14 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Letter to George, from Gene, Burnett, Wisconsin, January 22, 1862

An item in the George Woodard and Gene Smith letters ...
Woodard, George T., -1864, Smith, Gene E.   +1 more
core  

Gene-gene interaction among cell adhesion genes and risk of nonsyndromic cleft lip with or without cleft palate in Chinese case-parent trios. [PDF]

Mol Genet Genomic Med, 2019
Liu D, Wang M, Yuan Y, Schwender H, Wang H, Wang P, Zhou Z, Li J, Wu T, Zhu H, Beaty TH.   +10 more
europepmc   +1 more source