Results 251 to 260 of about 11,702,420 (293)

Gene–environment interaction in dyslipidemia

Current Opinion in Lipidology, 2015
Recent genome-wide association studies have identified numerous common genetic variants associated with plasma lipid traits and have provided new insights into the regulation of lipoprotein metabolism including the identification of novel biological processes.
Christopher B, Cole, Majid, Nikpay, Ruth, McPherson   +2 more
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Gene-Environment Interaction and Cancer

2020
It is widely recognized that cancer is an epigenetic disease. Hypomethylation of cytosine residues of CpG dinucleotides, site-specific CpG promoter hypermethylation, altered histone methylation and acetylation and dysregulation of miRNAs have been shown in several types of cancers.
D'Esposito V., Ambrosio M. R., Perruolo G., Libutti M., Formisano P.   +4 more
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Gene-Environment Interaction and Suicidal Behavior

Journal of Psychiatric Practice, 2009
Studies have increasingly shown that gene-environment interactions are important in psychiatry. Suicidal behavior is a major public health problem. Suicide is generally considered to be a multi-determined act involving various areas of proximal and distal risk.
ROY A, SARCHIAPONE, Marco, CARLI V.
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Gene-Environment Interactions in Obesity

2009
Obesity is a global and growing problem. The detrimental health consequences of obesity are significant and include co-morbidities such as diabetes, cancer and coronary heart disease. The marked rise in obesity observed over the last three decades suggests that behavioural and environmental factors underpin the chronic mismatch between energy intake ...
Marion M, Hetherington, Joanne E, Cecil
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Gene–environment interactions in ocular diseases

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2009
Degenerative ocular diseases are widespread in the population and represent a major cause of reversible and irreversible blindness. Scientific evidences have been accumulating supporting the role of genotoxic damage and gene environment interactions in the pathogenesis of these diseases mainly including glaucoma, age-related macular degeneration, and ...
SACCA' SC, BOLOGNESI C, BATTISTELLA A, BAGNIS A, IZZOTTI, ALBERTO   +4 more
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Flavors in Gene–Environment Interactions

Epidemiology, 2007
In this issue, Noel Weiss (Epidemiology. 2007;18:429-430) presents the argument that gene-environment interaction should be approached through analysis of genetic effects within strata of environmental exposure, rather than the analysis of environmental effects within strata of genetic variants. Both approaches depend on a pair of 2-by-2 tables.
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Gene-environment interactions in asthma

Journal of Allergy and Clinical Immunology, 2009
Asthma is a complex disease, and its incidence is determined by an intricate interplay of genetic and environmental factors. The identification of novel genes for asthma suggests that many genes with small effects rather than few genes with strong effects contribute to the development of asthma.
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Gene-Environment Interactions in Pancreatic Cancer

Pancreatology, 2001
Exocrine pancreatic cancer remains a major cause of cancer death in Western populations. Despite many efforts, little is known about its etiology. Tobacco is the only established cause, although the proportion of cases of exocrine pancreatic cancer attributed to it is only 30%. A family history of pancreatic cancer accounts for 10% of the cases of this
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Gene-Environment Interactions

2012
Gene-environment interactions are considered in Chap. 10, which focuses on a 2×2×2 table. The expressions of odds ratios for the genetic effect, the environmental factor effect, and the gene-environment interaction are given. More general cases for gene and environmental factors are briefly discussed. Three common tests for gene-environment interaction
Gang Zheng, Yaning Yang, Xiaofeng Zhu, Robert C. Elston   +3 more
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Gene–environment interactions

2018
ADHD is highly heritable, but environmental factors also play significant roles in disease aetiology and outcome. Genetic and environmental influences are likely to show different types of interplay, with gene–environment interactions (G×E) playing a part.
Barbara Franke, Jan K. Buitelaar
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