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Gene-Environment Interactions in Obesity
2009Obesity is a global and growing problem. The detrimental health consequences of obesity are significant and include co-morbidities such as diabetes, cancer and coronary heart disease. The marked rise in obesity observed over the last three decades suggests that behavioural and environmental factors underpin the chronic mismatch between energy intake ...
Marion M, Hetherington, Joanne E, Cecil
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Gene–environment interactions in ocular diseases
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2009Degenerative ocular diseases are widespread in the population and represent a major cause of reversible and irreversible blindness. Scientific evidences have been accumulating supporting the role of genotoxic damage and gene environment interactions in the pathogenesis of these diseases mainly including glaucoma, age-related macular degeneration, and ...
SACCA' SC +4 more
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Flavors in Gene–Environment Interactions
Epidemiology, 2007In this issue, Noel Weiss (Epidemiology. 2007;18:429-430) presents the argument that gene-environment interaction should be approached through analysis of genetic effects within strata of environmental exposure, rather than the analysis of environmental effects within strata of genetic variants. Both approaches depend on a pair of 2-by-2 tables.
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Gene-environment interactions in asthma
Journal of Allergy and Clinical Immunology, 2009Asthma is a complex disease, and its incidence is determined by an intricate interplay of genetic and environmental factors. The identification of novel genes for asthma suggests that many genes with small effects rather than few genes with strong effects contribute to the development of asthma.
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Gene-Environment Interactions in Pancreatic Cancer
Pancreatology, 2001Exocrine pancreatic cancer remains a major cause of cancer death in Western populations. Despite many efforts, little is known about its etiology. Tobacco is the only established cause, although the proportion of cases of exocrine pancreatic cancer attributed to it is only 30%. A family history of pancreatic cancer accounts for 10% of the cases of this
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2012
Gene-environment interactions are considered in Chap. 10, which focuses on a 2×2×2 table. The expressions of odds ratios for the genetic effect, the environmental factor effect, and the gene-environment interaction are given. More general cases for gene and environmental factors are briefly discussed. Three common tests for gene-environment interaction
Gang Zheng +3 more
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Gene-environment interactions are considered in Chap. 10, which focuses on a 2×2×2 table. The expressions of odds ratios for the genetic effect, the environmental factor effect, and the gene-environment interaction are given. More general cases for gene and environmental factors are briefly discussed. Three common tests for gene-environment interaction
Gang Zheng +3 more
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2005
Foreword. Acknowledgments. Contributors. PART I. Chapter 1. Introduction (Lucio G. Costa and David L. Eaton). Chapter 2. Ecogenetics: Historical Perspectives (Gilbert S. Omenn and Arno G. Motulsky). Chapter 3. Tools of Ecogenetics (Theo K. Bammler, Federico M. Farin, and Richard P. Beyer). Chapter 4.
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Foreword. Acknowledgments. Contributors. PART I. Chapter 1. Introduction (Lucio G. Costa and David L. Eaton). Chapter 2. Ecogenetics: Historical Perspectives (Gilbert S. Omenn and Arno G. Motulsky). Chapter 3. Tools of Ecogenetics (Theo K. Bammler, Federico M. Farin, and Richard P. Beyer). Chapter 4.
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2018
ADHD is highly heritable, but environmental factors also play significant roles in disease aetiology and outcome. Genetic and environmental influences are likely to show different types of interplay, with gene–environment interactions (G×E) playing a part.
Barbara Franke, Jan K. Buitelaar
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ADHD is highly heritable, but environmental factors also play significant roles in disease aetiology and outcome. Genetic and environmental influences are likely to show different types of interplay, with gene–environment interactions (G×E) playing a part.
Barbara Franke, Jan K. Buitelaar
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Understanding Gene–Environment Interactions
Genetic Testing and Molecular Biomarkers, 2011Amanda, Field +2 more
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Gene-environment Interaction in Spherical Equivalent and Myopia: An Evidence-based Review
Ophthalmic Epidemiology, 2022Xiyan Zhang, Qiao Fan, Fengyun Zhang
exaly

