Results 151 to 160 of about 860,814 (258)

<i>CCNE1</i> Gene Amplification Might Be Associated with Lymph Node Metastasis of Gastric Cancer. [PDF]

Genes (Basel)
Nishikubo H, Kawabata K, Sano T, Kanei S, Aoyama R, Ma D, Imanishi D, Sakuma T, Maruo K, Yamamoto Y, Fan C, Yashiro M.   +11 more
europepmc   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

SARS-CoV-2 and Swabs: Disease Severity and the Numbers of Cycles of Gene Amplification, Single Center Experience. [PDF]

Children (Basel), 2023
Falsaperla R, Sortino V, Collotta AD, Marino S, Pavone P, Grassi L, Privitera GF, Ruggieri M.   +7 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Impact of DNA Extraction and 16S rRNA Gene Amplification Strategy on Microbiota Profiling of Faecal Samples. [PDF]

Int J Mol Sci
Toto F, Scanu M, Gramegna M, Putignani L, Del Chierico F.   +4 more
europepmc   +1 more source

Gene Amplification and the Extrachromosomal Circular DNA. [PDF]

Genes (Basel), 2021
Shimizu N.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

IncL plasmid-mediated dissemination of OXA-48 β-lactamase and bla _CTX-M-15 gene amplification identified via long-read sequencing in carbapenem-resistant Enterobacterales. [PDF]

JAC Antimicrob Resist
Prasad S, Dratvova B, Gryndlerova A, Brajerova M, Kabelikova P, Tkadlec J, Drevinek P, Krutova M.   +7 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Template switching during DNA replication is a prevalent source of adaptive gene amplification. [PDF]

Elife
Chuong JN, Ben Nun N, Suresh I, Matthews JC, De T, Avecilla G, Abdul-Rahman F, Brandt N, Ram Y, Gresham D.   +9 more
europepmc   +1 more source