Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Glioblastoma with cerebrospinal fluid dissemination and MYC gene amplification: A transitional or atypical glioblastoma with primitive neuronal components. [PDF]
Zhang W +5 more
europepmc +1 more source
Electrochemical Gene Amplification Signal Detection of Disposable Biochips Using Electrodes. [PDF]
Kim GR +4 more
europepmc +1 more source
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
EGFR gene amplification in IDH-wildtype glioblastomas: an integrative bioinformatic and histopathological analysis using immunohistochemistry and fluorescence in situ hybridization. [PDF]
Oukhdouch A, Zinbi B, Sellami S, Rais H.
europepmc +1 more source
Deep learning to automatically evaluate HER2 gene amplification status from fluorescence in situ hybridization images. [PDF]
Xue T +13 more
europepmc +1 more source
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
<i>CCNE1</i> Gene Amplification Might Be Associated with Lymph Node Metastasis of Gastric Cancer. [PDF]
Nishikubo H +11 more
europepmc +1 more source

