Results 221 to 230 of about 860,814 (258)

Gene amplification and tumor progression

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1993
Proto-oncogenes are the genes which are most frequently found amplified in human tumor cells. Acquisition of a drug-resistant phenotype by gene amplification is frequent for in-vitro cultured cells but is very rare in human tumors. Proto-oncogenes amplified in human tumors belong essentially to one of three families (erbB, ras, myc) or to the 11q13 ...
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Gene Amplification and qRT-PCR

2014
This chapter includes methods for the use of the polymerase chain reaction (PCR) with Pseudomonas, and several specific tips for their successful application in this organism. The first part of the chapter includes methods for purifying genomic DNA from, and amplifying genes from, Pseudomonas, in addition to methods which describe how to prepare a cell
Cerith, Jones, Alain, Filloux
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Gene amplification and gene correction in somatic cells

Cell, 1982
We used gene transfer to identify frequent genetic rearrangements responsible for activating mutant genes in mammalian cells. We transformed an aprt- tk- cell with a plasmid containing a wild-type aprt gene and a truncated, promoterless tk gene. Transformants that integrate a single copy of this plasmid exhibit the aprt+ phenotype but remain tk-.
J M, Roberts, R, Axel
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Gene amplifications in osteosarcoma—CGH microarray analysis

Genes, Chromosomes and Cancer, 2004
AbstractLittle is known about the genomic alterations underlying osteosarcoma. We performed a genomewide high‐resolution gene copy number analysis of 22 osteosarcoma samples using comparative genomic hybridization on a cDNA microarray that contained cDNA clones of about 13,000 genes.
Atiye, Jassu, Wolf, Maija, Kaur, Sippy, Monni, Outi, Bohling, Tom, Kivioja, Aarne, Tas, Eva, Serra, Massimo, Tarkkanen, Maija, Knuutila, Sakari   +10 more
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Gene amplification in human gliomas

Glia, 1995
AbstractGliomas represent the largest group of primary brain tumors in adults. The astrocytic variants are the most common and the adult forms are histologically stratified into three malignancy grades. Of these glioblastoma is the most common and the most malignant; it has also been best studied by molecular genetics and cytogenetics.
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Gene Amplification

2008
Stewart B. Peck, Carol C. Mapes, Netta Dorchin, John B. Heppner, Eileen A. Buss, Gustavo Moya-Raygoza, Marjorie A. Hoy, Gerald Franz, Alfred M. Handler, Marjorie A. Hoy, John L. Capinera, John B. Heppner, Bella R. Striganova, John B. Heppner, John B. Heppner, John B. Heppner, John B. Heppner, Marta Goula, Tobin D. Northfield, Russell F. Mizell, John B. Heppner, John B. Heppner, John B. Heppner, John B. Heppner, Rami Kfir, William A. Overholt, Des E. Conlong, Mamoudou Sétamou, Fritz Schulthess, William A. Overholt, Rami Kfir, Kitty F. Cardwell, Fritz Schulthess, Rami Kfir, Zeyaur R. Khan, William A. Overholt, Régis Goebel, Kia Rashidan, Claude Guertin, Jean Cabana, Doug Downie, George M. Orphanides, John L. Capinera, John L. Capinera, John L. Capinera, Steven Arthurs, John L. Capinera, Norma E. Sánchez, María L. De Wysiecki, John B. Heppner, Yousif Aldryhim, James C. Dunford, Kelly R. Sims, John L. Capinera, John L. Capinera, Gregory A. Sword, Eric W. Riddick, Paul M. Choate, Wayne Brewer   +58 more
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Gene Amplification Mechanisms

2006
Michelle, Debatisse, Bernard, Malfoy
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Gene Amplification in Dipteran Chromosomes

1987
The giant polytene chromosomes characteristic of many Dipteran cells allow fundamental nuclear processes occurring during development to be directly visualized. Polytene chromosomes afford a detailed picture of “large-scale” structures within developmentally regulated interphase cells — features extending over more than about 5–10 kb of chromosomal DNA.
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Gene Amplification

2011
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ESR1 gene amplification: another mechanism regulating the cellular levels of ERα

Nature Reviews Cancer, 2011
Ke-Da Yu, Zhi-Ming Shao, Yu Ke-Da
exaly