Pharmacokinetics of infigratinib and its active metabolites in Chinese patients with advanced gastric cancer harboring FGFR2 gene amplification. [PDF]
Yuan J+19 more
europepmc +1 more source
Isothermal gene amplification coupled MALDI-TOF MS for SARS-CoV-2 detection. [PDF]
Han G, Lin Q, Yi J, Lyu Q, Ma Q, Qiao L.
europepmc +1 more source
Transfection of Mouse Fibroblast Cells with a Promoterless Herpes Simplex Virus Thymidine Kinase Gene: Number of Integrated Gene Copies and Structure of Single and Amplified Gene Sequences [PDF]
Wolfgang Pülm, Rolf Knippers
openalex +1 more source
Amplification of the rRNA Genes in Tetrahymena
M.-C. Yao, J. G. Gall, E. Blackburn
openaire +3 more sources
Real‐world genomic landscape of colon and rectal cancer
We confirmed enrichment of RTK alterations in patients with RAS/BRAF‐wt tumors and of PI3K pathway alterations in RAS/BRAF‐altered tumors with 51 982 real‐world tissue comprehensive genomic profiling (CGP) samples in CRC. In a subset of 140 patients with both tissue and liquid results, the sensitivity of liquid for results found by tissue was 100% when
Markus Schulze+7 more
wiley +1 more source
A Novel Digital PCR Assay for Accurate Detection and Differentiation of Focal and Non-Focal Subtypes of Mesenchymal-Epithelial Transition (<i>MET</i>) Gene Amplification in Lung Cancer. [PDF]
Shek RCM+12 more
europepmc +1 more source
Systematic Analysis of Copy Number Variations in the Pathogenic Yeast Candida parapsilosis Identifies a Gene Amplification in RTA3 That is Associated with Drug Resistance. [PDF]
Bergin SA+11 more
europepmc +1 more source
Overproduction of the B1 Subunit of Ribonucleotide Reductase with Gene Amplification. [PDF]
Åke Larsson+4 more
openalex +1 more source
Dexmedetomidine suppresses glucose‐stimulated insulin secretion in pancreatic β‐cells
Dexmedetomidine decreases insulin release and affects glucose metabolism; however, the specific mechanism remains largely unknown. This study shows clinically relevant doses of dexmedetomidine suppressed glucose‐stimulated insulin secretion. There was no significant difference in oxygen consumption rate, intracellular ATP levels, or caspase‐3/7 ...
Munenori Kusunoki+5 more
wiley +1 more source
EGFR, HER2, and MET gene amplification and protein expression profiles in biliary tract cancer and their prognostic significance. [PDF]
Kim Y+6 more
europepmc +1 more source