Results 301 to 310 of about 8,130,594 (350)

A Peptide Nucleic Acid‐Functionalized Heterojunction Thin Film Transistor as a Scalable and Reusable Platform for Label‐Free Detection of MicroRNA

open access: yesAdvanced Functional Materials, EarlyView.
A miniaturized, label‐free, and enzyme‐free biosensor (miR‐TFT) enables direct electrical detection of microRNA (miRNA) with single‐nucleotide specificity and a detection limit of 0.6 fM. Built on a tri‐channel In2O3/ZnO heterojunction and functionalized with bespoke peptide nucleic acid (PNA) probes, the device is robust, reusable, and compatible with
Wejdan S. Al Ghamdi   +5 more
wiley   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

open access: yesAdvanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim   +4 more
wiley   +1 more source
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Gene amplification in cancer

Trends in Genetics, 2006
Gene amplification is a copy number increase of a restricted region of a chromosome arm. It is prevalent in some tumors and is associated with overexpression of the amplified gene(s). Amplified DNA can be organized as extrachromosomal elements, as repeated units at a single locus or scattered throughout the genome.
openaire   +2 more sources

GENE AMPLIFICATION IN LEISHMANIA

Annual Review of Microbiology, 1991
INTRODUCTION . . . . . . . . . . . . .. . .... . . .... . . . . . . . . . . . . . . . . . . . . . .. . ... . . . .. . . . .. . . .. . . .. .. . .. . . . . . . . . . . 417 A Leishmania Primer 4 1 8 The Leishmania Genome and Circular DNAs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
openaire   +2 more sources

GENE AMPLIFICATION

Annual Review of Biochemistry, 1984
G R, Stark, G M, Wahl
  +6 more sources

Clinical Resistance to STI-571 Cancer Therapy Caused by BCR-ABL Gene Mutation or Amplification

Science, 2001
M. Gorre   +6 more
semanticscholar   +1 more source

Gene Amplification Mechanisms

2006
Michelle, Debatisse, Bernard, Malfoy
openaire   +2 more sources

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