Results 181 to 190 of about 8,793,913 (366)
CG dinucleotide clusters in MHC genes and in 5′ demethylated genes [PDF]
Mark L. Tykocinski, Edward E. Max
openalex +1 more source
Cluster analysis and display of genome-wide expression patterns.
M. Eisen+3 more
semanticscholar +1 more source
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker+16 more
wiley +1 more source
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa+14 more
wiley +1 more source
A rapid combinatorial assembly method for gene cluster characterisation illuminates glidobactin biosynthesis. [PDF]
Calcott MJ, Kröger J, Ackerley DF.
europepmc +1 more source
Regulation of the apolipoprotein gene cluster by a long noncoding RNA.
P. Halley+9 more
semanticscholar +1 more source
The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause+6 more
wiley +1 more source
Pseudomonadal itaconate degradation gene cluster encodes enzymes for methylsuccinate utilization. [PDF]
Gonner L, Cassens EA, König S, Berg IA.
europepmc +1 more source