Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui +3 more
wiley +1 more source
Identification of a novel complex variant in a patient involving the α-globin gene cluster by third-generation sequencing. [PDF]
Liu H +6 more
europepmc +1 more source
Structurally diverse molecular deletions in the beta-globin gene cluster exhibit an identical phenotype on interaction with the beta S- gene [PDF]
NP Anagnou +3 more
openalex +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Subfunctionalization and epigenetic regulation of a biosynthetic gene cluster in <i>Solanaceae</i>. [PDF]
Priego-Cubero S +8 more
europepmc +1 more source
Genetic and Physical Analyses of a Cluster of Genes Essential for Xanthan Gum Biosynthesis in Xanthomonas campestris [PDF]
openalex +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Rediscovery of viomellein as an antibacterial compound and identification of its biosynthetic gene cluster in dermatophytes. [PDF]
Ninomiya A +7 more
europepmc +1 more source

