Results 291 to 300 of about 9,738,594 (396)

Fast, flexible gene cluster family delineation with IGUA

Larralde M, Blom J, Gourlé H, Carroll LM, Zeller G.   +4 more
europepmc   +1 more source

antiSMASH 8.0: extended gene cluster detection capabilities and analyses of chemistry, enzymology, and regulation. [PDF]

Nucleic Acids Res
Blin K, Shaw S, Vader L, Szenei J, Reitz ZL, Augustijn HE, Cediel-Becerra JDD, de Crécy-Lagard V, Koetsier RA, Williams SE, Cruz-Morales P, Wongwas S, Segurado Luchsinger AE, Biermann F, Korenskaia A, Zdouc MM, Meijer D, Terlouw BR, van der Hooft JJJ, Ziemert N, Helfrich EJN, Masschelein J, Corre C, Chevrette MG, van Wezel GP, Medema MH, Weber T.   +26 more
europepmc   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Elucidation of novel turnagainolides and their biosynthetic gene cluster in <i>Bacillus subtilis</i>. [PDF]

Appl Environ Microbiol
Li P, Han S, Wang M, Zhang X, Zhi S, Jin M, Jokela J, He S, Liu L.   +8 more
europepmc   +1 more source

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen, Yuying Zhang, Heyu Zhang, Jinming Zhang, Ningning Wang, Xintong Guo, Yicong Liu, Yue Liu, Xiangsong Zhang, Ziyi Chen, Guanzhong Ni   +10 more
wiley   +1 more source

The distribution and evolution of muscarine and the ibotenic acid biosynthetic gene cluster within the genus <i>Amanita</i> section <i>Amanita</i> revealed by phylogenomics. [PDF]

IMA Fungus
Su YT, He ZM, Yang YZ, Xu F, Lai MM, Yang ZL, Zhang P, Chen ZH.   +7 more
europepmc   +1 more source

Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis–Associated Interstitial Lung Disease

Arthritis Care &Research, EarlyView.
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla, Robert Lafyatis, Kevin F. Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J. Kass   +13 more
wiley   +1 more source

Phylogenomic Identification of a Highly Conserved Copper-Binding RiPP Biosynthetic Gene Cluster in Marine <i>Microbulbifer</i> Bacteria. [PDF]

ACS Chem Biol
Tang Y, Zhong W, Fu L, Asante E, Kostenko A, Vidya FNU, Mandelare-Ruiz P, Adeogun TT, Anderson GP, Edmonds BE, Fang O, Han M, Hollingsworth AS, Ingham AR, Kirby CR, Landrum A, Mack CR, Nobari NS, Oswald EJ, Polevoy CL, Sharifian Y, So TJ, Stokes JR, Thompson RS, Vuthamaraju R, Wang EC, Yang WH, Onstine AE, Paul VJ, Wu R, Aron AT, Agarwal V.   +31 more
europepmc   +1 more source

Heterogeneity of Rheumatoid Arthritis–Associated Interstitial Lung Disease by Longitudinal Forced Vital Capacity Trajectory and Associations With Disease Outcomes

Arthritis Care &Research, EarlyView.
Objective We aimed to identify unique disease trajectories within rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) based on longitudinal forced vital capacity (FVC) values and their associated clinical outcomes. Methods We performed a cohort study of RA‐ILD within the Veterans Health Administration from 1999 to 2021.
Bryant R. England, Yangyuna Yang, Punyasha Roul, Tate M. Johnson, Scott M. Matson, Grant W. Cannon, Brian C. Sauer, Jeffrey R. Curtis, Joshua F. Baker, Ted R. Mikuls   +9 more
wiley   +1 more source

Profiling structural variations of the α-globin gene cluster by the single molecule real-time sequencing: remarkable diversity of the spectrum with rare and novel variants identified in a large Chinese cohort. [PDF]

Hum Genet
Wei D, Cheng Z, Wei W, Gui C, Liu J, Chen H, Ma Y, Peng X, Yu D, Huang Y, Lai Y, Gui B.   +11 more
europepmc   +1 more source