Results 311 to 320 of about 9,198,934 (404)

Biointerface Membranes Orchestrating Site‐Specific Osteoimmunomodulatory and Antibacterial Effects for Enhanced Osseous Regeneration in Periodontal Therapy

Advanced Functional Materials, EarlyView.
Here, a biointerface membrane engineered with site‐specific interfacial properties is developed. During implantation between gingival and bone defect, the membrane creates a pro‐osteogenic microenvironment, precisely modulates cellular activities at each biointerface, and facilitates the orchestration of complex healing events, ultimately leading to ...
Yuwei Zhu, Tingting Wang, Jing Zhu, Bingtian Zhao, Bingyang Dai, Xiaoyue Zhang, Wei Liu, Cheng Yang, Cheng Dong, Ren Liu, Lei Zhao, Jun Wang, Peilei Shi, To Ngai   +13 more
wiley   +1 more source

Editorial: Vector-based gene delivery in cancer immunotherapy. [PDF]

Front Immunol
Cheng N, Yang X, Chen D, Xu C.
europepmc   +1 more source

Modulation of Vibrio cholerae gene expression through conjugative delivery of engineered regulatory small RNAs

Pilar Menendez-Gil, Diana Veleva, Mollie Virgo, Jige Zhang, Rita Ramalhete, Brian T. Ho   +5 more
openalex   +1 more source

Self‐Feeding of Engineered Tissues via Controlled Glucose Release Facilitates Survival and Vascularization of Living Implants

Advanced Functional Materials, EarlyView.
ABSTRACT Engineering living matter has great clinical potential to deliver functional replacement organs. However, clinical translation remains hampered by the current inability to maintain viability of clinically relevant‐sized constructs. During the pre‐vascular phase, implants rely on nutrient diffusion for survival, which is insufficient at ...
Melvin Gurian, Iris E. Allijn, Laura Veenendaal, Nicole Bassous, Su Ryon Shin, Jeroen Leijten   +5 more
wiley   +1 more source

WFS1 gene delivery rescues visual function in a mouse model of Wolfram syndrome

Jagodzinska J, Péquignot M, Sarzi E, Quiles M, Cazevieille C, Müller A, Koks S, Delettre C.   +7 more
europepmc   +1 more source

A Simple and Safe Protocol for Intra-Testicular Gene Delivery in Neonatal Mice Using a Convenient Isoflurane-Based Anesthesia System. [PDF]

BioTech (Basel)
Morohoshi K, Ohba M, Sato M, Nakamura S.
europepmc   +1 more source

Growth factor gene delivery for Alzheimer's disease: from animal models to clinical trials

, 2009
Mark H. Tuszynski, Alan H. Nagahara, Brock E. Schroeder, G. Coppola, L Wang, Armin Blesch, Edward Rockenstein, Daniel H. Geschwind, Eliezer Masliah, Edward H. Koo, Ayaka Chiba   +10 more
openalex   +1 more source

MagPiezo: A Magnetogenetic Platform for Remote Activation of Endogenous Piezo1 Channels in Endothelial Cells

Advanced Functional Materials, EarlyView.
MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández, Mariarosaria De Simone, Yilian Fernández‐Afonso, Daniel Garcia‐Gonzalez, Pablo Martínez‐Vicente, Thomas van Zanten, Raluca M. Fratila, Maria Moros   +7 more
wiley   +1 more source

Protamine-Based Nanotherapeutics for Gene Delivery to Glioblastoma Cells. [PDF]

Mol Pharm
Barrios-Esteban S, Reimóndez-Troitiño S, Cabezas-Sainz P, de la Fuente M, Sánchez L, Rahman R, Alexander C, Garcia-Fuentes M, Csaba NS.   +8 more
europepmc   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source