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Recent progress in nanomaterials for gene delivery applications.
Biomaterials Science, 2016Nanotechnology-based gene delivery is the division of nanomedicine concerned with the synthesis, characterization, and functionalization of nanomaterials to be used in targeted-gene delivery applications.
Erhan Keles +4 more
semanticscholar +1 more source
Journal of Controlled Release
Gene delivery has revolutionized conventional medical approaches to vaccination, cancer, and autoimmune diseases. However, current gene delivery methods are limited to either intravenous administration or direct local injections, failing to achieve well biosafety, tissue targeting, drug retention, and transfection efficiency for desired therapeutic ...
Wentao, Zhang +5 more
openaire +2 more sources
Gene delivery has revolutionized conventional medical approaches to vaccination, cancer, and autoimmune diseases. However, current gene delivery methods are limited to either intravenous administration or direct local injections, failing to achieve well biosafety, tissue targeting, drug retention, and transfection efficiency for desired therapeutic ...
Wentao, Zhang +5 more
openaire +2 more sources
2002
Gene therapy bases its rationale on the transfer of genetic components (genes or fragments thereof) into somatic cells, with the aim of preventing, correcting, or healing various types of disorders. After this introductory sentence, the reader likely expects us to begin discussing some of the marvellous achievements in setting up the tools that allow ...
Maurizio Ceppi, Sandro Rusconi
openaire +2 more sources
Gene therapy bases its rationale on the transfer of genetic components (genes or fragments thereof) into somatic cells, with the aim of preventing, correcting, or healing various types of disorders. After this introductory sentence, the reader likely expects us to begin discussing some of the marvellous achievements in setting up the tools that allow ...
Maurizio Ceppi, Sandro Rusconi
openaire +2 more sources
Ultrasensitive pH Triggered Charge/Size Dual-Rebound Gene Delivery System.
Nano letters (Print), 2016A facile strategy is developed to construct an ultrasensitive pH triggered charge/size dual-rebound gene delivery system for efficient tumor treatment.
Xiuwen Guan +5 more
semanticscholar +1 more source
Gene and Oligonucleotide Delivery
Drug Metabolism and Pharmacokinetics, 2022Shigeru, Kawakami, Hidetoshi, Arima
openaire +2 more sources
2005
Polymeric gene delivery systems have been developed to overcome problems caused by viral carriers. They are low cytotoxic, have no size limit, are convenient in handling, of low cost and reproducible. A Terplex gene delivery system consisting of plasmid DNA, low density lipoprotein and hydropholized poly-L-lysine was designed and characterized.
openaire +3 more sources
Polymeric gene delivery systems have been developed to overcome problems caused by viral carriers. They are low cytotoxic, have no size limit, are convenient in handling, of low cost and reproducible. A Terplex gene delivery system consisting of plasmid DNA, low density lipoprotein and hydropholized poly-L-lysine was designed and characterized.
openaire +3 more sources
In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector
Science, 1996L. Naldini +7 more
semanticscholar +1 more source