Results 191 to 200 of about 1,025,168 (353)

Data from Inhibition of AMPK and Krebs Cycle Gene Expression Drives Metabolic Remodeling of <i>Pten</i>-Deficient Preneoplastic Thyroid Cells

, 2023
Valeria G. Antico Arciuch, Marika A. Russo, Kristy S. Kang, Antonio Di Cristofano   +3 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Is Gene Drive Research Losing Traction? [PDF]

Am J Trop Med Hyg
Lanzaro GC, Kormos AM.
europepmc   +1 more source

Image 12_ASR gene family: a case of tandem-drive evolution.jpeg

Nicolle Louise Ferreira Barros (21535367), João Pedro Carmo Filgueiras (14282129), Thomaz Stumpf Trenz (14243120), Guilherme Weber (21535370), Andreia Carina Turchetto-Zolet (10469668), Marcia Margis-Pinheiro (114189)   +5 more
openalex   +1 more source

Case report: NUP98::LEDGF fusion gene drives malignant hematological tumor with mixed immunological phenotype [PDF]

Song Xue, Jiaqi Chen, Tong Wang, Lina Zhang, Man Chen, Hui-Peng Sun, Xingyu Cao   +6 more
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Modeling Control of Invasive Fire Ants by Gene Drive. [PDF]

Adv Sci (Weinh)
Liu Y, Champer SE, Haller BC, Champer J.
europepmc   +1 more source

Expansion of Adhesion Genes Drives Pathogenic Adaptation of Nematode-Trapping Fungi

, 2020
Xinglai Ji, Zefen Yu, Jinkui Yang, Jianping Xu, Ying Zhang, Shu-Qun Liu, Cheng‐Gang Zou, Juan Li, Lianming Liang, Ke‐Qin Zhang   +9 more
openalex   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Gene-drive-capable mosquitoes suppress patient-derived malaria in Tanzania. [PDF]

Nature
Habtewold T, Lwetoijera DW, Hoermann A, Mashauri R, Matwewe F, Mwanga R, Kweyamba P, Maganga G, Magani BP, Mtama R, Mahonje MA, Tambwe MM, Tarimo F, Chennuri PR, Cai JA, Del Corsano G, Capriotti P, Sasse P, Moore J, Hudson D, Manjurano A, Tarimo B, Vlachou D, Moore S, Windbichler N, Christophides GK.   +25 more
europepmc   +1 more source