Results 261 to 270 of about 519,971 (295)

Gene drive systems for insect disease vectors

Nature Reviews Genetics, 2006
The elegant mechanisms by which naturally occurring selfish genetic elements, such as transposable elements, meiotic drive genes, homing endonuclease genes and Wolbachia, spread at the expense of their hosts provide some of the most fascinating and ...
Steven P Sinkins, Fred Gould, Sinkins Steven P   +2 more
exaly   +2 more sources

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Incorporating ecology into gene drive modelling

Ecology Letters, 2023
AbstractGene drive technology, in which fast‐spreading engineered drive alleles are introduced into wild populations, represents a promising new tool in the fight against vector‐borne diseases, agricultural pests and invasive species. Due to the risks involved, gene drives have so far only been tested in laboratory settings while their population‐level
Jaehee Kim, Keith D. Harris, Isabel K. Kim, Shahar Shemesh, Philipp W. Messer, Gili Greenbaum   +5 more
openaire   +2 more sources

Genes drive organisms and slippery slopes

Pathogens and Global Health, 2022
The bioethical debate about using gene drives to alter or eradicate wild populations has focused mostly on issues concerning short-term risk assessment and management, governance and oversight, and public and community engagement, but has not examined big-picture- 'where is this going?'-questions in great depth. In other areas of bioethical controversy,
David B, Resnik, Raul F, Medina, Fred, Gould, George, Church, Jennifer, Kuzma   +4 more
openaire   +2 more sources

Gene drives and the EU

elni Review, 2020
With the discovery of the CRISPR/Cas9 method in 2012, the global research on gene drives - the deliberate release of genetically modified animals and plants into the environment - increased spectacularly, as the new methods are seen in particular as means to extinct vector-transmitted diseases such as malaria or dengue fever, or support agricultural ...
openaire   +1 more source

Genes that drive invasion and migration in Drosophila

Current Opinion in Genetics & Development, 2004
Successful cell migration depends on the careful regulation of the timing of movement, the guidance of motile cells, and cytoskeletal and adhesive changes within the cells. This review focuses on genes that act cell-autonomously to promote these aspects of cell migration in Drosophila.
Michelle, Starz-Gaiano, Denise J, Montell   +1 more
openaire   +2 more sources

Gene Drives

2021
Reagan Mudziwapasi, Ringisai Chekera, Clophas Zibusiso Ncube, Irvonnie Shoko, Berlinda Ncube, Thandanani Moyo, Jeffrey Godfrey Chimbo, Jemethious Dube, Farai Faustos Mashiri, Moira Amanda Mubani, Duncan Maruta, Charity Chimbo, Mpumuzi Masuku, Ryman Shoko, Rutendo Patricia Nyamusamba, Fortune Ntengwa Jomane   +15 more
openaire   +1 more source

The ethical landscape of gene drive research

Bioethics, 2019
AbstractGene drive technology has immense potential. The ability to bypass the laws of Mendelian inheritance and almost ensure the transmission of specific genetic material to future generations creates boundless possibilities. But alongside these boundless possibilities are major social and ethical issues.
openaire   +2 more sources

A natural gene drive system confers reproductive isolation in rice

Cell, 2023
Yehui Xiong, Siqi Cheng, Yunlu Tian
exaly  

Gene-Drive

Veloxsci, 2020
openaire   +1 more source

Review of gene drive modelling and implications for risk assessment of gene drive organisms

Ecological Modelling, 2023
Johannes L Fries, Carina R Lalyer, Bernd Giese   +2 more
exaly