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On the Multiple Gene Duplication Problem [PDF]

open access: yes, 1998
A fundamental problem in computational biology is the determination of the correct species tree for a set of taxa given a set of (possibly contradictory) gene trees. In recent literature, the DUPLICATION/ LOSS model has received considerable attention. Here one measures the similarity/dissimilarity between a set of gene trees by counting the number of ...
Michael R. Fellows   +2 more
openaire   +2 more sources

Role of gene duplication in evolution [PDF]

open access: yesGenome, 1989
It is now known that many multigene and supergene families exist in eukaryote genomes: multigene families with uniform copy members like genes for ribosomal RNA, those with variable members like immunoglobulin genes, and supergene families such as those for various growth factor and hormone receptors.
Tomoko Ohta
openaire   +3 more sources
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Duplication of haemoglobin genes

Biochimie, 1972
Resume L'etude de l'hemoglobine humaine a ete particulierement fructueuse dans la definition des genes de structure. La reconnaissance du fait que plus d'un locus peut intervenir dans le controle genetique d'une chaine polypeptidique a conduit a reexaminer certaines idees generalement acceptees.
S R, Hollán, R T, Jones, R D, Koler
openaire   +2 more sources

Duplications in theDMD gene

Human Mutation, 2006
The detection of duplications in Duchenne (DMD)/Becker Muscular Dystrophy (BMD) has long been a neglected issue. However, recent technological advancements have significantly simplified screening for such rearrangements. We report here the detection and analysis of 118 duplications in the DMD gene of DMD/BMD patients.
S J, White   +9 more
openaire   +2 more sources

Gene Duplication and Evolution

Science, 2001
Lynch and Conery ([1][1]) presented one of the first serious efforts to study the evolutionary fate of gene duplication using genomic sequence data. Their analysis led to several interesting observations, particularly with respect to the rate of gene duplication in eukaryotic genomes and ...
M, Long, K, Thornton
openaire   +2 more sources

Retention of duplicated genes in evolution

Trends in Genetics, 2022
Gene duplication is a prevalent phenomenon across the tree of life. The processes that lead to the retention of duplicated genes are not well understood. Functional genomics approaches in model organisms, such as yeast, provide useful tools to test the mechanisms underlying retention with functional redundancy and divergence of duplicated genes ...
Elena, Kuzmin   +2 more
openaire   +2 more sources

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