Sophora genomes provide insight into the evolution of alkaloid metabolites along with small-scale gene duplication. [PDF]
Kang YJ, Park H, Lee Y, Yoon S, Kwak M.
europepmc +1 more source
Evolution by gene duplication and compensatory advantageous mutations.
Takehiro Ohta
openalex +2 more sources
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
wiley +1 more source
Genome-Wide Identification, Gene Duplication, and Expression Pattern of <i>NPC2</i> Gene Family in <i>Parnassius glacialis</i>. [PDF]
Zhu Z+6 more
europepmc +1 more source
Weight Cycling Deregulates Eating Behavior in Mice via the Induction of Durable Gut Dysbiosis
Weight cycling in Humans is suspected to dysregulate eating behavior. Mice submitted to body weight cycling by alternating western‐type and regular chow diets display increased hedonic appetite when exposed to a palatable diet, reminiscent of binge‐eating episodes.
Mélanie Fouesnard+13 more
wiley +1 more source
This study identifies a super‐enhancer‐driven transcriptional regulatory circuit comprising BCL6, SMAD3, and NFIB that cooperate to drive cholesterol synthesis via SREBF2/HMGCR/FDFT1 activation and regulate CDK2/CCND3 for cell cycle control. Targeting this circuit with BI‐3802 or downstream inhibitors (Fatostatin/Lovastatin) overcomes abiraterone ...
Liling Jiang+18 more
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The Establishment of Complement System Is from Gene Duplication and Domain Shuffling. [PDF]
Sun J, Liu C, Wang L, Song L.
europepmc +1 more source
Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague
The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia+12 more
wiley +1 more source
Evolution, Gene Duplication, and Expression Pattern Analysis of CrRLK1L Gene Family in Zea mays (L.). [PDF]
Wang K+9 more
europepmc +1 more source