Results 331 to 340 of about 7,473,287 (361)
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Improving gene-editing nucleases
Nature Methods, 2012A flurry of recent papers report refinements to the activity and the assembly of engineered nucleases.
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2020
Cystic fibrosis therapeutics have advanced steadily over the past half century, increasing life expectancy from pre-school ages into the fourth and fifth decades of life. New, small molecule pharmacologic therapies that modulate CFTR biosynthesis or activity are proving to be quite effective for many CF patients, indicating that intervention at the ...
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Cystic fibrosis therapeutics have advanced steadily over the past half century, increasing life expectancy from pre-school ages into the fourth and fifth decades of life. New, small molecule pharmacologic therapies that modulate CFTR biosynthesis or activity are proving to be quite effective for many CF patients, indicating that intervention at the ...
openaire +2 more sources
A path to efficient gene editing
Nature Medicine, 2018Signaling by the tumor-suppressor protein p53 antagonizes CRISPR–Cas9 gene editing of human pluripotent stem cells and immortalized human retinal pigment epithelial cells.
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RNA-targeting and gene editing therapies for transthyretin amyloidosis
Nature Reviews Cardiology, 2022Alberto Aimo +9 more
semanticscholar +1 more source
2019
This chapter will broadly cover the newest genome editing technology, clustered regularly interspaced short palindromic repeats (CRISPR), and CRISPR-associated system (Cas), as a critical tool for a modern research laboratory. Multiplex gene mutagenesis, tissue-specific gene disruption, DNA insertions, transcriptional activation, transcriptional ...
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This chapter will broadly cover the newest genome editing technology, clustered regularly interspaced short palindromic repeats (CRISPR), and CRISPR-associated system (Cas), as a critical tool for a modern research laboratory. Multiplex gene mutagenesis, tissue-specific gene disruption, DNA insertions, transcriptional activation, transcriptional ...
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2019
This is an ethical reflection for students on an issue in gene editing. The case study asks students to reflect on material in the two linked articles. Also included is the grading rubric.
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This is an ethical reflection for students on an issue in gene editing. The case study asks students to reflect on material in the two linked articles. Also included is the grading rubric.
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Debate on Germline Gene Editing
Human Gene Therapy Methods, 2016Cartier-Lacave N. +7 more
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