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Messy Genetic Algorithm for evolving mathematical function evaluating variable length gene regulatory networks

2013 IEEE Congress on Evolutionary Computation, 2013
Evolutionary algorithms (EAs) have been successfully used in many studies for evolving both the structure and parameters of biological networks including gene regulatory networks that demonstrate different functionalities. However, most of these studies have used only mutation as the genetic operator in the evolutionary framework, perhaps due to the ...
Dhammika Suresh Hettiarachchi   +2 more
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Abstract 4852: Performances evaluation of algorithms for identifying differentially expressed genes in RNA-seq data

Cancer Research, 2015
Abstract Introduction RNA sequencing (RNA-seq) has rapidly become one of the main methods to study transcriptome. It has become an important and popular issue to identify biomarkers based on their differential expression patterns in NGS data. Currently, more than 10 different algorithms can be used to detect differentially
Chin-Ting Wu   +4 more
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Evaluation and Improving Hypergraph Based Learning Algorithm over Data Integration Problem for Cancer Related Genes

2012 International Conference on Advances in Computing and Communications, 2012
Reliable predictive model build using semi supervised learning utilising classification algorithm has evolved rapidly in successful cancer treatment. In order to optimise the data integration problem, such as hypergraph based learning to integrate microarray gene expressions and protein interactions for predicting cancer outcome, novice optimization ...
Seena Mary Augusty, Sminu Izudheen
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Deconer: A comprehensive and systematic evaluation toolkit for reference-based cell type deconvolution algorithms using gene expression data

2023
AbstractIn recent years, computational methods for quantifying cell type proportions from transcription data have gained significant attention, particularly those reference-based methods which have demonstrated high accuracy. However, there is currently a lack of comprehensive evaluation and guidance for available reference-based deconvolution methods ...
Wei Zhang   +7 more
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Extending meta-learning framework for clustering gene expression data with component-based algorithm design and internal evaluation measures

International Journal of Data Mining and Bioinformatics, 2016
Class retrieval in gene expression microarray data analysis is highly challenging task. Because of high class imbalance, highly dimensional feature space and small number of samples most of the algorithms fail to capture real complex structures in data 'golden standard'.
Vukićević, Milan   +3 more
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Performance Evaluation of Subspace-based Algorithm in Selecting Differentially Expressed Genes and Classification of Tissue Types from Microarray Data

The 2006 IEEE International Joint Conference on Neural Network Proceedings, 2006
This paper presents the implementation and evaluation of subspace-based clustering algorithm for robust selection of differentially expressed genes as well as the classification of tissue types from microarray data. The performance of the proposed algorithm is compared against other well known clustering algorithms and the quality of clusters is ...
J.S. Shaik, M. Yeasin
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Evaluation of next‐generation sequencing‐based clonality analysis of T‐cell receptor gamma gene rearrangements based on a new interpretation algorithm

International Journal of Laboratory Hematology, 2018
AbstractIntroductionT‐cell receptor gene (TRG) rearrangement profiling is an essential component of the workup at diagnosis of T‐cell malignancies. TRG amplification by polymerase chain reaction (PCR) and analysis by capillary electrophoresis (PCR‐CE) is mostly widely used but is hampered by a subjective interpretation of its results and possible false‐
Friedel Nollet   +6 more
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Gene expression programming algorithm based on multi-threading evaluator

Journal of Computer Applications, 2013
Sheng-qiao NI   +3 more
openaire   +1 more source

Examing and Evaluating Dimension Reduction Algorithms for Classifying Alzheimer’s Diseases using Gene Expression Data

2021 17th International Conference on Mobility, Sensing and Networking (MSN), 2021
Shunbao Li   +2 more
openaire   +1 more source

A Fast Genetic Algorithm Based on Single Gene Evaluation Fitness Mechanism for Job-Shop Scheduling Problem

2013
The Job Shop Scheduling Problem (JSSP) is one of the most general and difficult of all traditional scheduling problems. Search based on traditional ghenetic algorithms has a major drawback: large computational time and memory usage if a large population and / or a large number of generations are used but on the other hand larger population and larger ...
Janeš, Gordan   +2 more
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