Results 21 to 30 of about 411,688 (293)

Synstable Fusion: A Network-Based Algorithm for Estimating Driver Genes in Fusion Structures

open access: yesMolecules, 2018
Gene fusion structure is a class of common somatic mutational events in cancer genomes, which are often formed by chromosomal mutations. Identifying the driver gene(s) in a fusion structure is important for many downstream analyses and it contributes to ...
Mingzhe Xu   +5 more
doaj   +1 more source

Comparison of five supervised feature selection algorithms leading to top features and gene signatures from multi-omics data in cancer

open access: yesBMC Bioinformatics, 2022
Background As many complex omics data have been generated during the last two decades, dimensionality reduction problem has been a challenging issue in better mining such data. The omics data typically consists of many features. Accordingly, many feature
Tapas Bhadra   +3 more
doaj   +1 more source

New Bio-Marker Gene Discovery Algorithms for Cancer Gene Expression Profile

open access: yesIEEE Access, 2019
Several hybrid gene selection algorithms for cancer classification that employ bio-inspired evolutionary wrapper algorithm have been proposed in the literature and show good classification accuracy.
Nada Almugren, Hala M. Alshamlan
doaj   +1 more source

Machine learning techniques for identification of carcinogenic mutations, which cause breast adenocarcinoma

open access: yesScientific Reports, 2022
Breast adenocarcinoma is the most common of all cancers that occur in women. According to the United States of America survey, more than 282,000 breast cancer patients are registered each year; most of them are women.
Asghar Ali Shah   +4 more
doaj   +1 more source

A Key Protein Recognition Algorithm Based on High-order Complex Protein Network [PDF]

open access: yesInternational Journal Bioautomation, 2022
Although the existing protein recognition methods have improved the recognition accuracy of key proteins to a certain extent, they have ignored the biological features of the proteins.
Xiaojing Wang
doaj   +1 more source

Gene selection algorithms for microarray data based on least squares support vector machine

open access: yesBMC Bioinformatics, 2006
Background In discriminant analysis of microarray data, usually a small number of samples are expressed by a large number of genes. It is not only difficult but also unnecessary to conduct the discriminant analysis with all the genes.
Suganthan PN, Tang E Ke, Yao Xin
doaj   +1 more source

Large-scale event extraction from literature with multi-level gene normalization [PDF]

open access: yes, 2013
Text mining for the life sciences aims to aid database curation, knowledge summarization and information retrieval through the automated processing of biomedical texts.
Ananiadou, Sophia   +10 more
core   +3 more sources

Author Impact: Evaluations, Predictions, and Challenges

open access: yesIEEE Access, 2019
Author impact evaluation and prediction play a key role in determining rewards, funding, and promotion. In this paper, we first introduce the background of the author impact evaluation and prediction. Then, we review the recent developments of the author
Fuli Zhang, Xiaomei Bai, Ivan Lee
doaj   +1 more source

Comparative evaluation of isoform-level gene expression estimation algorithms for RNA-seq and exon-array platforms [PDF]

open access: yesBriefings in Bioinformatics, 2016
Given that the majority of multi-exon genes generate diverse functional products, it is important to evaluate expression at the isoform level. Previous studies have demonstrated strong gene-level correlations between RNA sequencing (RNA-seq) and microarray platforms, but have not studied their concordance at the isoform level.
Dapas, Matthew   +3 more
openaire   +2 more sources

Methods for evaluating clustering algorithms for gene expression data using a reference set of functional classes [PDF]

open access: yesBMC Bioinformatics, 2006
A cluster analysis is the most commonly performed procedure (often regarded as a first step) on a set of gene expression profiles. In most cases, a post hoc analysis is done to see if the genes in the same clusters can be functionally correlated. While past successes of such analyses have often been reported in a number of microarray studies (most of ...
Datta Somnath, Datta Susmita
openaire   +3 more sources

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