Results 41 to 50 of about 9,994,698 (300)

Molecular signatures of tumor progression in pancreatic adenocarcinoma identified by energy metabolism characteristics

open access: yesBMC Cancer, 2022
Background In this study, we performed a molecular evaluation of primary pancreatic adenocarcinoma (PAAD) based on the comprehensive analysis of energy metabolism-related gene (EMRG) expression profiles.
Cong Tan   +10 more
doaj   +1 more source

A Better Mechanistic Understanding of Big Data through an Order Search Using Causal Bayesian Networks

open access: yesBig Data and Cognitive Computing, 2022
Every year, biomedical data is increasing at an alarming rate and is being collected from many different sources, such as hospitals (clinical Big Data), laboratories (genomic and proteomic Big Data), and the internet (online Big Data).
Changwon Yoo   +3 more
doaj   +1 more source

Comparative evaluation of isoform-level gene expression estimation algorithms for RNA-seq and exon-array platforms [PDF]

open access: yesBriefings in Bioinformatics, 2016
Given that the majority of multi-exon genes generate diverse functional products, it is important to evaluate expression at the isoform level. Previous studies have demonstrated strong gene-level correlations between RNA sequencing (RNA-seq) and microarray platforms, but have not studied their concordance at the isoform level.
Matthew Dapas   +3 more
openaire   +2 more sources

The use of RNAIII inhibitory peptide in the treatment of elderly patients with staphylococcus aureus infection and construction of fuzzy mathematical model for curative effect evaluation

open access: yesResults in Physics, 2021
The study aims to explore application of RNAIII inhibiting peptide (RIP) and image information counting algorithm in the rehabilitation treatment plan of staphylococcus aureus infection in old people’s bone and joint.
Hong Ye   +7 more
doaj   +1 more source

Evolutionary Clustering Algorithm with Knowledge-Based Evaluation for Fuzzy Cluster Analysis of Gene Expression Profiles [PDF]

open access: yes, 2005
Clustering method, which groups thousands of genes by their similarities of expression levels, has been used for identifying unknown functions of genes. Fuzzy clustering method that is one category of clustering assigns one sample to multiple groups according to their membership degrees.
Han-Saem Park, Sung-Bae Cho
openaire   +1 more source

EGFAFS: A Novel Feature Selection Algorithm Based on Explosion Gravitation Field Algorithm

open access: yesEntropy, 2022
Feature selection (FS) is a vital step in data mining and machine learning, especially for analyzing the data in high-dimensional feature space. Gene expression data usually consist of a few samples characterized by high-dimensional feature space.
Lan Huang, Xuemei Hu, Yan Wang, Yuan Fu
doaj   +1 more source

A Hybrid Anti-notch/Goertzel Model for Gene Prediction in DNA Sequences [PDF]

open access: yesApplied Medical Informatics, 2014
Accurate detection of the exon regions in DNA sequences using signal processing tools has become a challenge in bioinformatics. In this paper, a hybrid Anti-notch/Goertzel algorithm has been presented for gene selection in DNA sequences.
Hamidreza Saberkari SABERKARI   +2 more
doaj  

RRHGE: A Novel Approach to Classify the Estrogen Receptor Based Breast Cancer Subtypes

open access: yesThe Scientific World Journal, 2014
Background. Breast cancer is the most common type of cancer among females with a high mortality rate. It is essential to classify the estrogen receptor based breast cancer subtypes into correct subclasses, so that the right treatments can be applied to ...
Ashish Saini, Jingyu Hou, Wanlei Zhou
doaj   +1 more source

An unsupervised text mining method for relation extraction from biomedical literature. [PDF]

open access: yesPLoS ONE, 2014
The wealth of interaction information provided in biomedical articles motivated the implementation of text mining approaches to automatically extract biomedical relations.
Changqin Quan, Meng Wang, Fuji Ren
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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