Results 51 to 60 of about 1,986,261 (302)
RRHGE: A Novel Approach to Classify the Estrogen Receptor Based Breast Cancer Subtypes
The Scientific World Journal, 2014 Background. Breast cancer is the most common type of cancer among females with a high mortality rate. It is essential to classify the estrogen receptor based breast cancer subtypes into correct subclasses, so that the right treatments can be applied to ...
Ashish Saini, Jingyu Hou, Wanlei Zhou
doaj +1 more source
An unsupervised text mining method for relation extraction from biomedical literature. [PDF]
PLoS ONE, 2014 The wealth of interaction information provided in biomedical articles motivated the implementation of text mining approaches to automatically extract biomedical relations.
Changqin Quan, Meng Wang, Fuji Ren
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A systematic evaluation of methods for tailoring genome-scale metabolic models
Cell Systems, 2017 Genome-scale models of metabolism can illuminate the molecular basis of cell phenotypes. Since many enzymes are only active in specific cell types, several algorithms use omics data to construct cell line- and tissue-specific metabolic models from genome-
S. Opdam +5 more
semanticscholar +1 more source
Inferring synteny between genome assemblies: a systematic evaluation
BMC Bioinformatics, 2017 Genome assemblies across all domains of life are being produced routinely. Initial analysis of a new genome usually includes annotation and comparative genomics.
Dang Liu, Martin Hunt, Isheng. J. Tsai
semanticscholar +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
Genome Medicine, 2022 Background Bacteria belonging to the genus Haemophilus cause a wide range of diseases in humans. Recently, H. influenzae was classified by the WHO as priority pathogen due to the wide spread of ampicillin resistant strains. However, other Haemophilus spp.
Margo Diricks +9 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz +7 more
wiley +1 more source
gdGSE: An algorithm to evaluate pathway enrichment by discretizing gene expression values
Computational and Structural Biotechnology JournalWe proposed gdGSE, a novel computational framework for gene set enrichment analysis. Unlike conventional methods that rely on continuous gene expression values, gdGSE employs discretized gene expression profiles to assess pathway activity. This approach effectively mitigates discrepancies caused by data distributions.
Jiangti Luo +5 more
openaire +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan +3 more
wiley +1 more source
CpG islands or CpG clusters: how to identify functional GC-rich regions in a genome?
BMC Bioinformatics, 2009 Background CpG islands (CGIs), clusters of CpG dinucleotides in GC-rich regions, are often located in the 5' end of genes and considered gene markers. Hackenberg et al.
Han Leng, Zhao Zhongming
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