Results 51 to 60 of about 191,482 (312)
A cDNA Microarray Gene Expression Data Classifier for Clinical Diagnostics Based on Graph Theory [PDF]
, 2011 Despite great advances in discovering cancer molecular profiles, the proper application of microarray technology to routine clinical diagnostics is still a challenge. Current practices in the classification of microarrays' data show two main limitations:
Stefano Di Carlo +5 more
core +1 more source
A Hybrid Anti-notch/Goertzel Model for Gene Prediction in DNA Sequences [PDF]
Applied Medical Informatics, 2014 Accurate detection of the exon regions in DNA sequences using signal processing tools has become a challenge in bioinformatics. In this paper, a hybrid Anti-notch/Goertzel algorithm has been presented for gene selection in DNA sequences.
Hamidreza Saberkari SABERKARI +2 more
doaj
RRHGE: A Novel Approach to Classify the Estrogen Receptor Based Breast Cancer Subtypes
The Scientific World Journal, 2014 Background. Breast cancer is the most common type of cancer among females with a high mortality rate. It is essential to classify the estrogen receptor based breast cancer subtypes into correct subclasses, so that the right treatments can be applied to ...
Ashish Saini, Jingyu Hou, Wanlei Zhou
doaj +1 more source
, 2004 Reeder J, Giegerich R. Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics. BMC Bioinformatics. 2004;5(1): 104.Background: The general problem of RNA secondary structure prediction under the widely ...
Reeder Jens +5 more
core +1 more source
Statistical inference of regulatory networks for circadian regulation [PDF]
, 2014 The work described in the present article is part of the TiMet project on linking the circadian clock to metabolism in plants. TiMet is a collaborative project (Grant Agreement 245143) funded by the European Commission FP7, in response to call FP7-KBBE ...
Aderhold, Andrej +2 more
core +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
A Dominated Coupling From The Past algorithm for the stochastic simulation of networks of biochemical reactions [PDF]
, 2008 24.02.14 KB. Ok to add published version to spiral, OA article.Background: In recent years, stochastic descriptions of biochemical reactions based on the Master Equation (ME) have become widespread. These are especially relevant for models involving gene
Mauricio Barahona +4 more
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Genome Medicine, 2022 Background Bacteria belonging to the genus Haemophilus cause a wide range of diseases in humans. Recently, H. influenzae was classified by the WHO as priority pathogen due to the wide spread of ampicillin resistant strains. However, other Haemophilus spp.
Margo Diricks +9 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Lineage tree analysis of immunoglobulin variable-region gene mutations in autoimmune diseases: chronic activation, normal selection [PDF]
, 2006 Autoimmune diseases show high diversity in the affected organs, clinical manifestations and disease dynamics. Yet they all share common features, such as the ectopic germinal centers found in many affected tissues.
Neta S. Zuckerman +29 more
core +1 more source