Results 251 to 260 of about 5,552,491 (299)

Optimizing reference gene selection for accurate gene expression analysis in plants. [PDF]

Plant Signal Behav
Xiong Z, Fu C, Huang S, Shi J.
europepmc   +1 more source

Targeted suppression of HO-2 gene expression impairs the innate anti-inflammatory and repair responses of the cornea to injury.

, 2011
Lars Bellner, Kiran Patil, Kirkland Castellano, Adna Halilovic, Michael W. Dunn, Michal L. Schwartzman   +5 more
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

A prognostic matrix gene expression signature defines functional glioblastoma phenotypes and niches. [PDF]

Commun Biol
Vishnoi M, Dereli Z, Yin Z, Kong EK, Kinali M, Thapa K, Babur O, Yun K, Abdelfattah N, Li X, Bozorgui B, Farach-Carson MC, Rostomily RC, Korkut A.   +13 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

SWI/SNF complexes modulate gene expression and the development of physical dependence to ethanol. [PDF]

Alcohol Clin Exp Res (Hoboken)
Mathies LD, Blackwell GG, Davies AG, Bettinger JC.   +3 more
europepmc   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Coordinated shifts in gene expression and regulation during mole-rat evolution

Daunesse M, Liorzou E, Parey E, Villar D, Berthelot C.   +4 more
europepmc   +1 more source

Analysis of common differential gene expression between rheumatoid arthritis and ulcerative colitis. [PDF]

PLoS One
Han PF, Cui WR, He FZ, Wu T, Liao CS.
europepmc   +1 more source