Results 251 to 260 of about 3,053,094 (318)

Collective Gene Expression Fluctuations Encode the Regulatory State of Cells

Olmeda F, Dang Y, Rost F, Schimmenti VM, Di Terlizzi I, Rulands S.   +5 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

The ontogeny of circadian clock gene expression during mouse fetal development. [PDF]

Biochem Biophys Rep
Stanton DL, Zhu L, Hansen PJ.
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

The transcriptome of the olm provides insights into its evolution and gene expression. [PDF]

Sci Rep
Holtze S, Demirtürk D, Ohlenschläger O, Hegele S, Siniuk K, Förste S, Raghavan V, Groth M, Bens M, Hassel N, Martel A, Lukač M, Cizelj I, Fischer M, Liu H, Hildebrandt TB, Hoffmann S, Sahm A.   +17 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Regulation of <i>NR4A2</i> Gene Expression and Its Importance in Neurodegenerative and Psychiatric Diseases. [PDF]

Int J Mol Sci
Ruiz-Sánchez E, Rojas C, Yescas Gómez P, Martínez-Rodríguez N, Ruiz-Chow ÁA, Nava-Ruiz C, Ibáñéz-Cervantes G, Arciniega-Martínez IM, Reséndiz-Albor AA, Rojas P.   +9 more
europepmc   +1 more source

Intravenous Delivery of Angiopep-Functionalized Polypropylenimine Dendriplex Enhances Gene Expression in the Brain. [PDF]

Int J Nanomedicine
Ali-Jerman H, Somani S, Al-Quraishi Z, Maeyouf K, Merkler M, Gerasimou S, Tate RJ, Sakata S, Mullin M, Irving C, Anderson GJ, Bame JR, MacKenzie G, McNeill G, Dufès C.   +14 more
europepmc   +1 more source

In vitro assessment of bacterial supernatants on hypothalamic gene expression: implications for appetite regulation. [PDF]

NPJ Biofilms Microbiomes
Cuesta-Marti C, Valderrama B, Bastiaanssen T, Cryan JF, Stanton C, O'Mahony SM, Clarke G, Schellekens H.   +7 more
europepmc   +1 more source

Conserved Gene Expression Plasticity in Development Is More Pervasive Than Expression Divergence Between Species of Caenorhabditis Nematodes. [PDF]

Evol Dev
Viswanath A, Fusca DD, Calarco JA, Cutter AD.   +3 more
europepmc   +1 more source