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Genes and Gene Expression

Clinical Orthopaedics and Related Research, 2000
Gene therapy is the process whereby a therapeutic protein is synthesized from a DNA molecule (gene) that has been inserted into the cells. The goal is to produce the desired protein in the proper quantity in the proper location. Successful designing of vectors for gene therapy requires knowledge of gene structure and regulation.
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Green fluorescent protein as a marker for gene expression.

Science, 1994
A complementary DNA for the Aequorea victoria green fluorescent protein (GFP) produces a fluorescent product when expressed in prokaryotic (Escherichia coli) or eukaryotic (Caenorhabditis elegans) cells. Because exogenous substrates and cofactors are not
M. Chalfie   +5 more
semanticscholar   +1 more source

HORMONES AND GENE EXPRESSION

Annual Review of Genetics, 1970
A hormone is an effector molecule produced in low concentration by one cell which evokes a physiological response in another. In vertebrates, nu­ merous classes of chemically unrelated compounds such as polypeptides, amino acids, amines, fatty acid derivatives, and steroids have hormonal activity. Certain of these substances probably are themselves the
David W. Martin, Gordon M. Tomkins
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Gene expression and aging

Mechanisms of Ageing and Development, 1993
Considerable amount of data has accumulated during the past few years showing several changes in gene expression as a function of age. However, the basic mechanism of aging still remains poorly understood. In this review, we have mainly analysed the data pertaining to the hypothesis that aging is associated with genetic instability and have attempted ...
Tatsuzo Oka   +2 more
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Gene Expression in Lactobacilli

2003
Lactobacilli have always occupied an important place in food production. Their properties are widely exploited all over the world, in particular, in the preparation of food products and beverages (Table 6.1). Lactic acid fermentation is one of the oldest techniques used for the preservation of highly perishable raw materials like milk, meat, and ...
Pouwels, P.H., Chaillou, S.
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Zinc and gene expression

Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1981
During the last two decades, zinc has been shown to be a functionally essential component of more than 120 enzymes and concurrently has been recognized as indispensible to normal cellular growth, development and differentiation of all species.
K. H. Falchuk, Bert L. Vallee
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Gene Expression in Eukaryotes

Science, 1981
Gene expression in eukaryotes is influenced by a wide variety of mechanisms including the loss, amplification, and rearrangement of genes. Genes are differentially transcribed, and the RNA transcripts are variably utilized. Multigene families regulate the amount, the diversity, and the timing of gene expression.
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The expression of immunoglobulin genes

Immunology Today, 1988
Abstract Transcription of antibody genes is restricted to lymphoid cells and is a process controlled by multiple DNA elements. However, modulation of expression during B-cell ontogeny is effected by post-transcriptional and post-translational processes.
Graham P. Cook, Michael S. Neuberger
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Collagen Gene Expression

American Journal of Respiratory Cell and Molecular Biology, 1989
Collagens are extracellular matrix proteins that play important structural roles in many tissues and organs. Thirteen types of collagen, the products of 23 genes, have been described. Most of the collagen genes are developmentally regulated; a given tissue or cell type expresses only a subset of the collagen genes.
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On the Expression of a Structural Gene

Journal of Molecular Biology, 1960
Experiments were made on the kinetics of β-galactosidase production by zygotes formed upon mating of inducible, lac+(Hfr z+i+), and constitutive, lac−(F−z−i−), strains of Escherichia coli K12. Enzyme formation commenced within two minutes of the time of injection of the z+ gene.
Arthur B. Pardee   +3 more
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