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Zinc and gene expression

Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1981
During the last two decades, zinc has been shown to be a functionally essential component of more than 120 enzymes and concurrently has been recognized as indispensible to normal cellular growth, development and differentiation of all species.
K. H. Falchuk, Bert L. Vallee
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Gene Expression in Eukaryotes

Science, 1981
Gene expression in eukaryotes is influenced by a wide variety of mechanisms including the loss, amplification, and rearrangement of genes. Genes are differentially transcribed, and the RNA transcripts are variably utilized. Multigene families regulate the amount, the diversity, and the timing of gene expression.
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Collagen Gene Expression

American Journal of Respiratory Cell and Molecular Biology, 1989
Collagens are extracellular matrix proteins that play important structural roles in many tissues and organs. Thirteen types of collagen, the products of 23 genes, have been described. Most of the collagen genes are developmentally regulated; a given tissue or cell type expresses only a subset of the collagen genes.
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Gene Expression in Heterozygotes

Nature, 1962
IN many cases a gene appears to function only by synthesizing a polypeptide chain through the mediation of ribonucleic acid (RNA), and hence controlling the synthesis of a protein. A mutation may cause a different polypeptide chain to be synthesized, for example, in the haemoglobinopathies, or may result in failure to produce a polypeptide chain at all.
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On the Expression of a Structural Gene

Journal of Molecular Biology, 1960
Experiments were made on the kinetics of β-galactosidase production by zygotes formed upon mating of inducible, lac+(Hfr z+i+), and constitutive, lac−(F−z−i−), strains of Escherichia coli K12. Enzyme formation commenced within two minutes of the time of injection of the z+ gene.
Arthur B. Pardee   +3 more
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Gene Expression in Atherogenesis

Thrombosis and Haemostasis, 2001
SummaryIt is conceivable that the extent and spatio-temperal expression of dozens or even a few hundred genes are significantly altered during the development and progression of atherosclerosis as compared to normal circumstances. Differential gene expression in vascular cells and in blood cells, due to gene-gene and gene-environment interactions can ...
E K Arkenbout   +2 more
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Expression of the Fibronectin Gene

American Journal of Respiratory Cell and Molecular Biology, 1989
Fibronectin (FN) is an extracellular matrix protein that acts as a substrate for cell migration and adhesion during development. FN adheres to cells through a dimeric membrane protein, the FN receptor. Antibodies to FN and synthetic peptides that inhibit FN-receptor interaction inhibit gastrulation, block neural crest cell migration, arrest cardiac ...
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Gene Express Inc

Pharmacogenomics, 2006
Gene Express, Inc. is a technology-licensing company and provider of Standardized Reverse Transcription Polymerase Chain Reaction (StaRT-PCR) services. Designed by and for clinical researchers involved in pharmaceutical, biomarker and molecular diagnostic product development, StaRT-PCR is a unique quantitative and standardized multigene expression ...
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Gene Expression in the Epididymis

1999
The epididymis is a tubular organ exhibiting vectorial functions of sperm concentration, maturation, transport, and storage. The molecular basis for these functions is poorly understood. However, it has become increasingly clear that regional differences along the length of the duct play a role in epididymal physiology and that region-specific gene ...
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Nutrition and Gene Expression

1999
Altering the expression of genes has become a rapidly evolving area of research in medicine. The realization that gene expression is important in a wide range of diseases, and not just in inherited disease, has resulted in recognition of the whole fi eld of gene expression as one that may bring new therapeutic options.
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