Results 91 to 100 of about 12,165,430 (302)

Comparative Enumeration Gene Expression [PDF]

, 2008
This paper is about differential gene expression measured by transcript counting methods such as SAGE or MPSS. It introduces two significance tests for detection of differential expressed tags: frequentist and Bayesian. Under the frequentist view, it is
Carlos A. D. E. B. Pereira, Carlos Pereira, Leonardo Varuzza   +2 more
core   +1 more source

Features of CDH1, CTNNB1 genes transcriptional activity and expression levels of E-cadherin, β-catenin proteins coded by these genes on the I, II, III, IV stages of colorectal adenocarcinoma development

Patologìâ, 2018
Aim – analysis of CDH1 and CTNNB1 genes mRNA expression levels and expression levels of E-cadherin, β-catenin proteins coded by these genes, and also their correlations with KRAS gene transcriptional activity level on the I, II, III, IV stages (pTNM) of ...
M. A. Shyshkin , V. O. Tumanskyi
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Temporal patterns of inflammatory gene expression in local tissues after banding or burdizzo castration in cattle [PDF]

, 2009
peer-reviewedBackground: Castration of male cattle has been shown to elicit inflammatory reactions and acute inflammation is initiated and sustained by the participation of cytokines.
Gath Vivian, Pang, Wanyong, Earley Bernadette, Sweeney, Torres, Sweeney Torres, Earley, Bernadette, Crowe Mark A, Gath, Vivian, Pang Wanyong, Crowe, Mark A   +9 more
core   +1 more source

Dosage regulation, and variation in gene expression and copy number of human Y chromosome ampliconic genes.

PLoS Genetics, 2019
The Y chromosome harbors nine multi-copy ampliconic gene families expressed exclusively in testis. The gene copies within each family are >99% identical to each other, which poses a major challenge in evaluating their copy number.
Rahulsimham Vegesna, Marta Tomaszkiewicz, Paul Medvedev, Kateryna D Makova   +3 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Association between changes in gene signatures expression and disease activity among patients with systemic lupus erythematosus

BMC Medical Genomics, 2019
Background We assessed the stability of BAFF, interferon, plasma cell and LDG neutrophil gene expression signatures over time, and whether changes in expression coincided with changes in SLE disease activity. Methods Two hundred forty-three patients with
Michelle Petri, Wei Fu, Ann Ranger, Norm Allaire, Patrick Cullen, Laurence S. Magder, Yuji Zhang   +6 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Effect of exogenous methyl jasmonate on the antioxidant system of Lentinula edodes mycelium under heat stress

四川大学学报. 自然科学版
To investigate the effects of exogenous methyl jasmonate （MeJA） on the antioxidant defense system of heat-stressed Lentinula edodes mycelia， this study used the ‘Xin 808’ strain as the experimental material. The mycelia were treated with 10 μmol·L-1 MeJA
CAI Chengkun, ZHENG Canlin, XIANG Quanju, CHEN Qiang, HE Maoqiang, GU Yunfu   +5 more
doaj  

Gene function contributes to gene expression levels in S. cerevisiae [PDF]

, 2018
ABSTRACT It is not understood what evolutionary factors drive some genes to be expressed at a higher level than others. Here, we hypothesized that a gene’s function plays an important role in setting expression level. First, we established that each S.
Hickman, Mark J., Jackson, Andrea, Smith, Abigail, Thornton, Julianne, Tursi, Amanda   +4 more
openaire   +1 more source