Results 101 to 110 of about 918,366 (270)

Time-course gene expression profiling of high glucose-induced endothelial cell apoptosis [PDF]

, 2014
Diabetes is a debilitating metabolic disorder resulting from hyperglycemia and glucose intolerance. High glucose-induced endothelial dysfunction is an important contributor to vascular disease in diabetes.
Weng, Julia T.Y.
core  

Spatial Transcriptomics Analysis of Spatially Dense Gene Expression Prediction [PDF]

arXiv
Spatial transcriptomics (ST) measures gene expression at fine-grained spatial resolution, offering insights into tissue molecular landscapes. Previous methods for spatial gene expression prediction usually crop spots of interest from pathology tissue slide images, and learn a model that maps each spot to a single gene expression profile.
arxiv  

Spectral analysis of gene expression profiles using gene networks [PDF]

arXiv, 2006
Microarrays have become extremely useful for analysing genetic phenomena, but establishing a relation between microarray analysis results (typically a list of genes) and their biological significance is often difficult. Currently, the standard approach is to map a posteriori the results onto gene networks to elucidate the functions perturbed at the ...
arxiv  

The Bimodality Index: A Criterion for Discovering and Ranking Bimodal Signatures from Cancer Gene Expression Profiling Data

Cancer Informatics, 2009
Motivation: Identifying genes with bimodal expression patterns from large-scale expression profiling data is an important analytical task. Model-based clustering is popular for this purpose. That technique commonly uses the Bayesian information criterion
Jing Wang, Sijin Wen, W. Fraser Symmans, Lajos Pusztai, Kevin R. Coombes   +4 more
doaj  

Genomic identification and expression profiling of DMP genes in oat (Avena sativa) elucidate their responsiveness to seed aging

BMC Genomics
Background The Domain of unknown function 679 membrane protein (DMP) family, which is unique to plants, plays a crucial role in reproductive development, stress response and aging.
Yuan Ma, Huan Liu, Jinglong Wang, Guiqin Zhao, Kuiju Niu, Xiangrui Zhou, Ran Zhang, Ruirui Yao   +7 more
doaj   +1 more source

Decoding Acute Myeloid Leukemia: A Clinician’s Guide to Functional Profiling

Diagnostics
Acute myeloid leukemia (AML) is a complex clonal disorder characterized by clinical, genetic, metabolomic, and epigenetic heterogeneity resulting in the uncontrolled proliferation of aberrant blood-forming precursor cells.
Prasad Iyer, Shaista Shabbir Jasdanwala, Yuhan Wang, Karanpreet Bhatia, Shruti Bhatt   +4 more
doaj   +1 more source

What does the Allen Gene Expression Atlas tell us about mouse brain evolution? [PDF]

arXiv, 2012
We use the Allen Gene Expression Atlas (AGEA) and the OMA ortholog dataset to investigate the evolution of mouse-brain neuroanatomy from the standpoint of the molecular evolution of brain-specific genes. For each such gene, using the phylogenetic tree for all fully sequenced species and the presence of orthologs of the gene in these species, we ...
arxiv  

Bayesian estimation of fold-changes in gene expression: the PFOLD algorithm and its uses in the analysis of complex expression profiles [PDF]

, 1999
Joachim Theilhaber, Steven Bushnell, Rainer Fuchs   +2 more
openalex   +1 more source

Surface-antigen expression profiling of B cell chronic lymphocytic leukemia: from the signature of specific disease subsets to the identification of markers with prognostic relevance

Journal of Translational Medicine, 2006
Studies of gene expression profiling have been successfully used for the identification of molecules to be employed as potential prognosticators.
Rupolo Maurizio, Benedetti Dania, Bulian Pietro, Dal Bo Michele, Bomben Riccardo, Degan Massimo, Sonego Paolo, Zucchetto Antonella, Del Poeta Giovanni, Campanini Renato, Gattei Valter   +10 more
doaj   +1 more source

GeneQuery: A General QA-based Framework for Spatial Gene Expression Predictions from Histology Images [PDF]

arXiv
Gene expression profiling provides profound insights into molecular mechanisms, but its time-consuming and costly nature often presents significant challenges. In contrast, whole-slide hematoxylin and eosin (H&E) stained histological images are readily accessible and allow for detailed examinations of tissue structure and composition at the microscopic
arxiv