Results 111 to 120 of about 2,498,124 (314)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Gene expression profiling in B-cell non-Hodgkin lymphomas

open access: yesIraqi Journal of Hematology
BACKGROUND: Gene expression profiling has become a fundamental tool in cancer diagnosis and management. B-cell non-Hodgkin lymphoma (B-NHL) is a group of malignant neoplasms originating from the lymphoid tissues, mainly the lymph nodes and the gene ...
Renas N. Saleem, Ahmed Khudair Yassin
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Gene expression profiling of flax (Linum usitatissimum L.) under edaphic stress [PDF]

open access: gold, 2016
Alexey A. Dmitriev   +14 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Common cell lysis procedures distort ribosome profiling analyses of gene expression

open access: yesGenome Biology
Ribosome profiling is a powerful technique used to study gene expression on a transcriptome-wide scale. It involves sequencing of mRNA fragments protected by ribosomes from ribonuclease digestion. The initial steps commonly involve cell lysis followed by
Aoife O’Connell   +6 more
doaj   +1 more source

Pectin as Carbon Source for Monilinia laxa Exoproteome and Expression Profiles of Related Genes [PDF]

open access: hybrid, 2020
Silvia Rodríguez‐Pires   +3 more
openalex   +1 more source

Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis.

open access: yesJournal of the National Cancer Institute, 2006
C. Sotiriou   +19 more
semanticscholar   +1 more source

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