Results 111 to 120 of about 2,789,846 (387)
A working model for cytoplasmic assembly of H/ACA snoRNPs
FEBS Letters, EarlyView.Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley +1 more source
Journal of Inflammation Research, 2020 Yifan Liu, Yantao Duan, Yousheng Li Department of General Surgery, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200011, People’s Republic of ChinaCorrespondence: Yousheng LiDepartment of General ...
Liu Y, Duan Y, Li Y
doaj
Gene Expression Value Prediction Based on XGBoost Algorithm
Frontiers in Genetics, 2019 Gene expression profiling has been widely used to characterize cell status to reflect the health of the body, to diagnose genetic diseases, etc. In recent years, although the cost of genome-wide expression profiling is gradually decreasing, the cost of ...
Wei Li +3 more
semanticscholar +1 more source
Gene Expression Profiling in Rheumatoid Arthritis [PDF]
, 2012 Rheumatoid arthritis (RA) is a systemic chronic inflammatory disease that primarily affects the joints. Aetiology of RA is unknown. Once symptoms are present RA manifests itself as a heterogeneous disease with a clinical spectrum ranging from mild to severe disease, and variable involvement in secondary organ systems.
Verweij, C.L., Vosslamber, S.
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FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Novel and unscrutinized immune entities of the zebrafish gut
FEBS Letters, EarlyView.Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies
Molecular Cancer, 2017 Background Colorectal cancer (CRC) cell lines are widely used pre-clinical model systems. Comprehensive insights into their molecular characteristics may improve model selection for biomedical studies.
Kaja C. G. Berg +13 more
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Unveiling the gene-expression profile of pollen
Genome biology, 2003 Four recent papers have characterized the transcription profile of pollen grains, showing striking differences between gene expression in pollen and other plant tissues. These studies increase the number of known pollen-expressed genes by as much as 50-fold and have identified many novel genes that are potentially pollen-specific.
da Costa-Nunes, J A, Grossniklaus, U
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FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
What can digital transcript profiling reveal about human cancers?
Brazilian Journal of Medical and Biological Research, 2003 Important biological and clinical features of malignancy are reflected in its transcript pattern. Recent advances in gene expression technology and informatics have provided a powerful new means to obtain and interpret these expression patterns.
J.M. Cerutti +2 more
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